Long‐term clinical, angiographic, and optical coherence tomography findings of Mg‐based bioresorbable scaffold in patients with acute coronary syndrome
| Autor: | Livia L. Gheorghe, Dolores Cañadas Pruaño, Gutierrez‐Barrios Alejandro, Antonio Gomez Menchero, Morales Ponce Francisco Jose, Uriel Martínez Capoccioni, Santiago Jesús Camacho Freire, Etel Silva, Germán Calle Pérez, Josep Gomez Lara, Teresa Bretones Del Pino |
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| Rok vydání: | 2021 |
| Předmět: |
Acute coronary syndrome
medicine.medical_specialty Lumen (anatomy) Context (language use) 030204 cardiovascular system & hematology Coronary Angiography Prosthesis Design 03 medical and health sciences Percutaneous Coronary Intervention 0302 clinical medicine Restenosis Internal medicine Absorbable Implants medicine Humans Radiology Nuclear Medicine and imaging Prospective Studies 030212 general & internal medicine Myocardial infarction Acute Coronary Syndrome Prospective cohort study Sirolimus medicine.diagnostic_test business.industry Drug-Eluting Stents General Medicine medicine.disease Stenosis Treatment Outcome Angiography Cardiology Cardiology and Cardiovascular Medicine business Tomography Optical Coherence |
| Zdroj: | Catheterization and Cardiovascular Interventions. 98 |
| ISSN: | 1522-726X 1522-1946 |
| DOI: | 10.1002/ccd.29557 |
| Popis: | BACKGROUND This study sought to evaluate the clinical outcomes of patients treated with magnesium-based bioresorbable scaffolds (MgBRS) in the context of acute coronary syndromes (ACS) at long-term follow-up (24 months). The study also aims to investigate the MgBRS performance by angiography and the healing and bioresorption pattern by optical coherence tomography (OCT) at 18 months. METHODS Between December 2016 and December 2018, a total of 90 patients admitted for ACS and treated with MgBRS (Magmaris, Biotronik AG, Bulach, Switzerland) were enrolled in a multicenter prospective study. Clinical follow-up was performed in all patients at 24 months and angiographic and OCT follow-up in 51.5% of patients at 18 months. Serial OCT was available in 33 patients (36.7%). RESULTS At a 2-year follow-up, 88.8% were free of symptoms, no cardiac death was reported, and the device-oriented composite event (DOCE): consisting of cardiac death, target vessel myocardial infarction, and target lesion revascularization (TLR) was 13.3%. Stent thrombosis and TLR were observed in 2.2 and 11.1%, respectively. Binary restenosis was observed in 21.7% of cases and in-stent late lumen loss was 0.61 ± 0.75 mm. By serial OCT imaging, the minimal lumen area was significantly reduced greater than 40% (from 6.12 ± 1.59 to 3.5 ± 1.55 mm2, p |
| Databáze: | OpenAIRE |
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