Outbreak of severe pseudorabies virus infection in pig-offal-fed farmed mink in Liaoning Province, China

Autor: Shuang Lv, Xijun Yan, Peng-Peng Xiao, Hu Bo, Xue Xianghong, Lian Shizhen, Shi Ning, Deng Xiaoyu, Lei Zhang, Yan Minghao, Hao Liu, Lu Rongguang, Hailing Zhang, Li Xintong
Rok vydání: 2016
Předmět:
Zdroj: Archives of Virology. 162:863-866
ISSN: 1432-8798
0304-8608
DOI: 10.1007/s00705-016-3170-7
Popis: An outbreak of severe pseudorabies virus (PRV) infection in farmed mink occurred in northern China in late 2014, causing significant economic losses in the local fur industry. Here, we report the first case of a PRV outbreak in mink in northeastern China, caused by feeding farmed mink with raw pork or organs contaminated by PRV. Mink infected with virulent PRV exhibited diarrhea, neurologic signs, and higher mortality, which can be misdiagnosed as highly pathogenic mink enteritis virus (MEV), canine distemper virus (CDV), and food poisoning. However, these were excluded as causative agents by PCR or bacteria isolation. The duration of disease was 3-7 days, and the mortality rate was 80-90%. PRV was characterized using indirect immunofluorescence assays (IFA) and electron microscopy (EM). Phylogenetic analysis based on full-length genome sequences and those of individual genes of this novel virus strain showed that it clustered in an independent branch with several other PRV isolates from China.
Databáze: OpenAIRE
Externí odkaz: