Element Mapping in Organic Samples Utilizing a Benchtop X-Ray Fluorescence Emission Tomography (XFET) System

Autor:	A. Groll, P.J. La Riviere, Phillip Vargas, Ling-Jian Meng, Jonathan George
Rok vydání:	2015
Předmět:	Physics Nuclear and High Energy Physics Tomographic reconstruction business.industry Detector X-ray fluorescence Fluorescence Article Synchrotron Imaging phantom law.invention Optics Nuclear Energy and Engineering law Medical imaging Tomography Electrical and Electronic Engineering business
Zdroj:	IEEE Transactions on Nuclear Science. 62:2310-2317
ISSN:	1558-1578 0018-9499
Popis:	X-ray fluorescence computed tomography (XFCT) is an emerging imaging modality that maps the three-dimensional distribution of elements, generally metals, in ex vivo specimens and potentially in living animals and humans. Building on our previous synchrotron-based work, we experimentally explored the use of a benchtop X-ray fluorescence computed tomography system for mapping trace-metal ions in biological samples. This system utilizes a scanning pencil-beam to stimulate the object and then relies on a detection system, with single or multiple slit apertures placed in front of position-sensitive X-ray detectors, to collect the fluorescence X-rays and to form 3-D elemental map without the need for tomographic imaging reconstruction. The technique was used to generate images of the elemental distributions of a triple-tube phantom and an osmium-stained zebrafish.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f84ff6cb36ee9c345a88cc12bb639f9 https://doi.org/10.1109/tns.2015.2465380 Zobrazit plný text záznamu