Relationships of a Novel Lyme Disease Spirochete, Borrelia spielmani sp. nov., with Its Hosts in Central Europe
| Autor: | Dania Richter, Franz-Rainer Matuschka, Daniela B. Schlee, Rainer Allgöwer |
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| Rok vydání: | 2004 |
| Předmět: |
Disease reservoir
Molecular Sequence Data Rodentia Spirochaetaceae Borrelia afzelii medicine.disease_cause Applied Microbiology and Biotechnology Rodent Diseases Lyme disease Borrelia Invertebrate Microbiology medicine Animals Humans Borrelia lusitaniae Disease Reservoirs Lyme Disease Ixodes Ecology biology Sequence Analysis DNA bacterial infections and mycoses biology.organism_classification medicine.disease Virology Tick Infestations Europe Arachnid Vectors Food Science Biotechnology Borrelia spielmanii |
| Zdroj: | Applied and Environmental Microbiology. 70:6414-6419 |
| ISSN: | 1098-5336 0099-2240 |
| Popis: | To determine whether the pathogenic variant of Lyme disease spirochetes, isolate A14S, is perpetuated in a particular reservoir-vector relationship, we screened vector ticks in various Central European sites for a related spirochete and determined its host association. A14S-like spirochetes infect numerous questing ticks in the Petite Camargue Alsacienne (PC). They frequently infect dormice, but no mice or voles. Garden dormice appear to be better reservoir hosts for A14S-like spirochetes than for Borrelia afzelii , because these spirochetes are retained longer and infect ticks more readily. Spirochetes associated with garden dormice in the PC site form a homologous entity with those isolated from a human patient in The Netherlands. Its unique biological relationship together with previous genetic characterization justifies designating this dormouse-associated genospecies as a distinct entity. Garden dormice serve as the main reservoir hosts of a novel genospecies, Borrelia spielmani sp. nov., one of several that cause Lyme disease in people. |
| Databáze: | OpenAIRE |
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