Effect of radiofrequency on patellar ligament repair of Wistar rats
| Autor: | Virgínia Oliveira Crema, Rosana Rosa Miranda Corrêa, Anna Cecília Dias Maciel Carneiro, Fabrizio Antonio Gomide Cardoso, Patrícia Helena Zanier-Gomes, Adriana Clemente Mendonça, Nanci Mendes Pinheiro |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
Complementary and Manual Therapy
medicine.medical_specialty Urology Physical Therapy Sports Therapy and Rehabilitation Lesion 03 medical and health sciences 0302 clinical medicine Patellar Ligament medicine Animals Rats Wistar 030222 orthopedics Wound Healing business.industry Patellar ligament Rehabilitation 030229 sport sciences musculoskeletal system Tendon Rats medicine.anatomical_structure Cross-Sectional Studies Complementary and alternative medicine Ligament Immunohistochemistry Collagen medicine.symptom business Wound healing Type I collagen Immunostaining |
| Zdroj: | Journal of bodywork and movement therapies. 24(4) |
| ISSN: | 1532-9283 |
| Popis: | This study aimed to evaluate the effects of radiofrequency (RF) on patellar ligament repair through the analysis of type I and III collagens and immunostaining for TGF-β3. To evaluate the effect of RF on patellar ligament repair of Wistar rats, cross-sectional incision (60% of the width - grade I) was performed in patellar ligaments of the groups: lesion (L, n = 7), treated with RF on the 5-day (5RF, n = 7) and 7-day (7RF, n = 7) post injury were compared to control group (C, n = 7). Histological evaluation, immunohistochemistry, morphometry and statistical analysis were performed. At 10 days post injury, ligament rupture were observed only in L. Active fibroblasts, type 3 collagen and TGF-β3 in L, 5RF and 7RF was significantly (p < 0.05) higher than control (C). Type 1 collagen was significantly (p < 0.05) higher in C than L, 5RF and 7RF. A positive correlation (p < 0.05) was observed: TGF-β3 vs active fibroblasts and TGF-β3 vs type 3 collagen; otherwise, negative correlation (p < 0.05): type I collagen vs TGF-β3. These results suggest that RF seemed to accelerate the wound healing process of the patellar ligament and may be used as a non-invasive treatment of partial ligament injuries. |
| Databáze: | OpenAIRE |
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