Biopsy of cervical lymph node does not impact the survival of nasopharyngeal carcinoma
| Autor: | Shi-Ping Yang, Zhao-Jun Li, Dan-Xia Chen, Chen-Lu Lian, San-Gang Wu, Ji-Fang Li, Ping Zhou |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
Male
lymph node biopsy Oncology Cancer Research medicine.medical_specialty Biopsy Lymph node biopsy histology Internal medicine Epidemiology Humans Medicine Radiology Nuclear Medicine and imaging Stage (cooking) Lymph node Research Articles RC254-282 medicine.diagnostic_test business.industry nasopharyngeal carcinoma Clinical Cancer Research Neoplasms. Tumors. Oncology. Including cancer and carcinogens Middle Aged medicine.disease Survival Analysis clinical practice medicine.anatomical_structure Nasopharyngeal carcinoma Cohort Propensity score matching Female Lymph Nodes prognosis business Research Article |
| Zdroj: | Cancer Medicine, Vol 10, Iss 19, Pp 6687-6696 (2021) Cancer Medicine |
| ISSN: | 2045-7634 |
| DOI: | 10.1002/cam4.4204 |
| Popis: | Purpose The optimal practice regarding cervical lymph node biopsy (CLNB) remains to be defined to provide the best clinical management in nasopharyngeal carcinoma (NPC). This study aimed to investigate the effect of CLNB on the survival of NPC patients. Methods Patients diagnosed with NPC from 2004 to 2015 were identified using the Surveillance, Epidemiology, and End Results database. Multivariate logistic regression, Kaplan–Meier method, Cox proportional hazards regression analysis, and propensity score matching (PSM) were used to determine the factors associated with CLNB and prognostic effect of CLNB of NPC. Results We included 1903 patients in this study. There were 321 (16.9%) and 1582 (83.1%) patients with and without CLNB, respectively. The percentage of CLNB was 19.4% in 2004 and was decreased to 8.6% in 2015 (p = 0.044). Patients diagnosed in later years (p = 0.008), older age (p The optimal practice regarding the cervical lymph node biopsy (CLNB) remains to be defined to provide the best clinical management in nasopharyngeal carcinoma (NPC). This study aimed to investigate the effect of CLNB on the survival of NPC patients using a population‐based cohort. Our study suggests that additional CLNB is not associated with increased risk of cancer‐specific mortality of NPC. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|