Behavior of squamous cell carcinoma of the floor of the mouth. Is supraomohyoid neck dissection sufficiently safe to manage clinically N0 patients?
| Autor: | Dario Sanchez Lopez, Jose Fernandez Solis, Almudena Cabello Serrano, Maria Roman Ramos, Paolo Cariati, Ildefonso Martinez Lara |
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| Rok vydání: | 2017 |
| Předmět: |
Adult
Male Poor prognosis medicine.medical_specialty medicine.medical_treatment Aggressive disease 03 medical and health sciences Young Adult 0302 clinical medicine Medicine Humans Basal cell Neoplasm Invasiveness Mouth Floor Aged Neoplasm Staging Retrospective Studies Floor of mouth business.industry Margins of Excision Neck dissection Level iv General Medicine 030206 dentistry Middle Aged Selective neck dissection Otorhinolaryngology 030220 oncology & carcinogenesis Lymphatic Metastasis Carcinoma Squamous Cell T-stage Neck Dissection Female Mouth Neoplasms Radiology Neoplasm Recurrence Local business |
| Zdroj: | Acta otorrinolaringologica espanola. 70(2) |
| ISSN: | 2173-5735 |
| Popis: | Aim The main aim of the present report is to study the behavior of SCC of the floor of the mouth. Materials and method A retrospective analysis was conducted using the records of patients diagnosed with squamous cell carcinoma of the floor of the mouth between 2000 and 2012 in the HUVN. Ninety-three patients with squamous cell carcinoma of the floor of the mouth treated with tumourectomy and selective neck dissection were included in the study. The pattern of distribution of cervical metastases and numerous histological features such as T-stage, N stage, surgical margins, tumor thickness, ECS (extracapsular spread) and vascular invasion were analyzed. Results Level I was the most affected level, followed by Level II. T stage, tumor thickness, and surgical margins showed a strong relationship with the risk of developing a local or cervical failure at follow-up. Overall survival was 52.7%. T stage, tumor thickness, N stage, recurrence, extracapsular spread, and vascular invasion were also associated with a poor prognosis. Conclusions SCC of the floor of the mouth is an aggressive disease even at early stages. Due to the low rate of positive nodes observed at level IV and V in clinically N0 patients, supraomohyoid neck dissection might be considered sufficiently safe in this group. |
| Databáze: | OpenAIRE |
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