Antimicrobial susceptibility of nine udder pathogens recovered from bovine clinical mastitis milk in Europe 2015–2016: VetPath results

Autor: Ian Morrissey, Rebecca Klee, Markus Rose, Farid El Garch, Anno de Jong, Myriam Youala, Benoît Valot, Shabbir Simjee, Beata Truszkowska, Didier Hocquet, Hilde Moyaert
Přispěvatelé: Vétoquinol, VetPath Study Group, CEESA, Centre Hospitalier Régional Universitaire de Besançon (CHRU Besançon), Laboratoire Chrono-environnement - CNRS - UBFC (UMR 6249) (LCE), Centre National de la Recherche Scientifique (CNRS)-Université de Franche-Comté (UFC), Université Bourgogne Franche-Comté [COMUE] (UBFC)-Université Bourgogne Franche-Comté [COMUE] (UBFC), IHMA, Monthey, Switzerland.
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Cattle Diseases
Microbial Sensitivity Tests
Biology
medicine.disease_cause
Antimicrobial resistance
Microbiology
03 medical and health sciences
Mammary Glands
Animal
Antibiotic resistance
Ampicillin
Clavulanic acid
Drug Resistance
Bacterial
medicine
Animals
Dairy cattle
Pirlimycin
Mastitis
Bovine
030304 developmental biology
0303 health sciences
Surveillance
Bacteria
General Veterinary
030306 microbiology
SCCmec
Minimum inhibitory concentrations
General Medicine
biochemical phenomena
metabolism
and nutrition
medicine.disease
Anti-Bacterial Agents
3. Good health
Mastitis
Europe
Penicillin
Dairying
Milk
[SDV.MP]Life Sciences [q-bio]/Microbiology and Parasitology
Streptococcus agalactiae
Bacterial mastitis pathogens
Cattle
Female
[SDV.MHEP]Life Sciences [q-bio]/Human health and pathology
medicine.drug
Zdroj: Veterinary Microbiology
Veterinary Microbiology, Elsevier, 2020, 245, pp.108644. ⟨10.1016/j.vetmic.2020.108644⟩
ISSN: 0378-1135
Popis: International audience; VetPath is an ongoing pan-European antimicrobial susceptibility monitoring programme collecting pathogens from diseased cattle, pigs and poultry not recently treated with antibiotics. Non-duplicate isolates (n = 1244) were obtained from cows with acute clinical mastitis in eight countries during 2015-2016 for centrally antimicrobial susceptibility testing according CLSI standards. Among Escherichia coli (n = 225), resistance was high to ampicillin and tetracycline, moderate to kanamycin and low to amoxicillin/clavulanic acid and cefazolin. The MIC50/90 of danofloxacin, enrofloxacin and marbofloxacin were 0.03 and 0.06 μg/mL. For Klebsiella spp. (n = 70), similar results were noted, except for ampicillin and kanamycin. We detected 3.7 % (11/295) Enterobacteriaceae isolates carrying an ESBL/AmpC gene. Staphylococcus aureus (n = 247) and coagulase-negative staphylococci (CoNS; n = 189) isolates were susceptible to most antimicrobials tested except to penicillin (25.1 and 29.1 % resistance). Two S. aureus and thirteen CoNS isolates harboured mecA gene. Streptococcus uberis isolates (n = 208) were susceptible to β-lactam antibiotics (87.1-94.7 % susceptibility), 23.9 % were resistant to erythromycin and 37.5 % to tetracycline. Resistance to pirlimycin was moderate. For Streptococcus dysgalactiae (n = 132) the latter figures were 10.6 and 43.2 %; pirlimycin resistance was low. MIC values for Streptococcus agalactiae, Trueperella pyogenes and Corynebacterium spp. were generally low. This current VetPath study shows that mastitis pathogens were susceptible to most antimicrobials with exceptions of staphylococci against penicillin and streptococci against erythromycin or tetracycline. For most antimicrobials, the percentage resistance and MIC50/90 values among the major pathogens were comparable to that of the preceeding VetPath surveys. This work highlights the high need to set additional clinical breakpoints for antimicrobials frequently used to treat mastitis.
Databáze: OpenAIRE
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