Equine acquired multiple acyl-CoA dehydrogenase deficiency (MADD) in 14 horses associated with ingestion of Maple leaves (Acer pseudoplatanus) covered with European tar spot (Rhytisma acerinum)
Autor: | J. H. van der Kolk, J.A. Dijkstra, Inge D. Wijnberg, M. G. M. de Sain-van der Velden, L. C. Kranenburg, J.J. van der Lugt, E. Gruys, M. Duran, Ronald J.A. Wanders, C.M. Westermann, Lambertus Dorland |
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Přispěvatelé: | Amsterdam Gastroenterology Endocrinology Metabolism, Laboratory Genetic Metabolic Diseases |
Jazyk: | angličtina |
Rok vydání: | 2010 |
Předmět: |
Male
Endocrinology Diabetes and Metabolism Carboxylic Acids Glycine Acer Biochemistry Microbiology Foodborne Diseases Endocrinology Tar (tobacco residue) Ascomycota Carnitine Genetics medicine Ingestion Animals Horses Multiple Acyl-CoA Dehydrogenase Deficiency Myopathy Multiple Acyl Coenzyme A Dehydrogenase Deficiency Molecular Biology Plant Diseases biology Chemistry Acyl CoA dehydrogenase Acer pseudoplatanus biology.organism_classification Plant Leaves Rhytisma acerinum biology.protein lipids (amino acids peptides and proteins) Female Horse Diseases medicine.symptom medicine.drug |
Zdroj: | Molecular genetics and metabolism, 101(2-3), 289-291. Academic Press Inc. |
ISSN: | 1096-7192 |
DOI: | 10.1016/j.ymgme.2010.06.019 |
Popis: | This case-series describes fourteen horses suspected of equine acquired multiple acyl-CoA dehydrogenase deficiency (MADD) also known as atypical myopathy of which seven cases were confirmed biochemically with all horses having had access to leaves of the Maple tree (Acer pseudoplatanus) covered with European tar spot (Rhytisma acerinum). Assessment of organic acids, glycine conjugates, and acylcarnitines in urine was regarded as gold standard in the biochemical diagnosis of equine acquired multiple acyl-CoA dehydrogenase deficiency. (C) 2010 Elsevier Inc. All rights reserved |
Databáze: | OpenAIRE |
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