Predictors for the Efficacy of Electroconvulsive Therapy
| Autor: | Aeilko H. Zwinderman, Ben A. Blansjaar, King H. Kho |
|---|---|
| Přispěvatelé: | Amsterdam Public Health, Epidemiology and Data Science |
| Rok vydání: | 2005 |
| Předmět: |
Male
medicine.medical_specialty Pediatrics Psychosis Bipolar Disorder medicine.medical_treatment behavioral disciplines and activities Medical Records Sex Factors Electroconvulsive therapy mental disorders medicine Humans Psychiatric hospital Treatment Failure Bipolar disorder Electroconvulsive Therapy Psychiatry Depression (differential diagnoses) Probability Retrospective Studies Psychiatric Status Rating Scales Depressive Disorder Major Psychotropic Drugs Age Factors Hamilton Rating Scale for Depression Retrospective cohort study Middle Aged medicine.disease Diagnostic and Statistical Manual of Mental Disorders Psychiatry and Mental health Logistic Models Treatment Outcome Major depressive disorder Female Psychology Selective Serotonin Reuptake Inhibitors Follow-Up Studies |
| Zdroj: | Journal of clinical psychiatry, 66(7), 894-899. Physicians Postgraduate Press Inc. |
| ISSN: | 0160-6689 |
| DOI: | 10.4088/jcp.v66n0712 |
| Popis: | Background Several variables have been suggested that can predict the efficacy of electro-convulsive therapy (ECT) in patients suffering from depression. The results of studies into these predictors for ECT efficacy are not consistent. Method In a retrospective chart review of patients suffering from major depressive disorder and bipolar disorder according to DSM-IV criteria who have been given ECT in a psychiatric hospital in the Netherlands, predictors for ECT efficacy were explored. Information was gathered for predictors including sex, age, diagnosis, presence of psychosis, duration of index episode, medication treatment failure prior to ECT, medication during ECT course, and ECT variables. ECT was given twice weekly from November 1997 to June 2002. The 17-item Hamilton Rating Scale for Depression (HAM-D) was applied at baseline and weekly during the course. Results Seventy-three patients suffering from unipolar or bipolar depression were given ECT in the study period, with 56 patients (77%) meeting antidepressant treatment history form criteria for medication treatment failure. With remission defined as a reduction of depressive symptoms of at least 60% from baseline and a HAM-D end score of less than 8, 48 patients (65.8%) remitted. Forward stepwise logistic regression analysis selected only duration of index episode as a significant predictor for ECT efficacy. Medication treatment failure was not found to be a significant predictor. The concurrent use of psychotropic medication during ECT did not influence the efficacy. Conclusion Duration of index episode was the only variable found to significantly predict the efficacy of ECT. |
| Databáze: | OpenAIRE |
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