Comparison ofin vitrobreast cancer visibility in analyser-based computed tomography with histopathology, mammography, computed tomography and magnetic resonance imaging

Autor: Mikko Tenhunen, Jani Keyriläinen, Christian Nemoz, Manuel Fernández, Aki Kangasmäki, Marjut Leidenius, Petri Sipilä, Alberto Bravin, Karl von Smitten, Pekka Virkkunen, Marja-Liisa Karjalainen-Lindsberg, Pekka Suortti
Přispěvatelé: Keyrilainen, J, Fernandez, M, Bravin, A, Karjalainen-Lindsberg, M, Leidenius, M, von Smitten, K, Tenhunen, M, Kangasmaki, A, Sipila, P, Nemoz, C, Virkkunen, P, Suortti, P
Rok vydání: 2011
Předmět:
Nuclear and High Energy Physics
medicine.medical_specialty
mammography
FIS/07 - FISICA APPLICATA (A BENI CULTURALI
AMBIENTALI
BIOLOGIA E MEDICINA)
Breast Neoplasms
Radiation Dosage
phase-contrast imaging
030218 nuclear medicine & medical imaging
03 medical and health sciences
breast cancer
0302 clinical medicine
Breast cancer
medicine
Humans
magnetic resonance imaging
Mammography
Medical physics
Breast
Instrumentation
Computed tomography laser mammography
Radiation
medicine.diagnostic_test
business.industry
Carcinoma
Ductal
Breast
Visibility (geometry)
Phase-contrast imaging
Cancer
computed tomography
Magnetic resonance imaging
medicine.disease
X-ray diffraction
3. Good health
Carcinoma
Lobular
030220 oncology & carcinogenesis
Female
Histopathology
Tomography
X-Ray Computed
X-ray optic
Nuclear medicine
business
Synchrotrons
Zdroj: Journal of Synchrotron Radiation. 18:689-696
ISSN: 1600-5775
0909-0495
Popis: High-resolution analyser-based X-ray imaging computed tomography (HR ABI-CT) findings on in vitro human breast cancer are compared with histopathology, mammography, computed tomography (CT) and magnetic resonance imaging. The HR ABI-CT images provided significantly better low-contrast visibility compared with the standard radiological images. Fine cancer structures indistinguishable and superimposed in mammograms were seen, and could be matched with the histopathological results. The mean glandular dose was less than 1 mGy in mammography and 12-13 mGy in CT and ABI-CT. The excellent visibility of in vitro breast cancer suggests that HR ABI-CT may have a valuable role in the future as an adjunct or even alternative to current breast diagnostics, when radiation dose is further decreased, and compact synchrotron radiation sources become available.
Databáze: OpenAIRE
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