Comparison ofin vitrobreast cancer visibility in analyser-based computed tomography with histopathology, mammography, computed tomography and magnetic resonance imaging
Autor: | Mikko Tenhunen, Jani Keyriläinen, Christian Nemoz, Manuel Fernández, Aki Kangasmäki, Marjut Leidenius, Petri Sipilä, Alberto Bravin, Karl von Smitten, Pekka Virkkunen, Marja-Liisa Karjalainen-Lindsberg, Pekka Suortti |
---|---|
Přispěvatelé: | Keyrilainen, J, Fernandez, M, Bravin, A, Karjalainen-Lindsberg, M, Leidenius, M, von Smitten, K, Tenhunen, M, Kangasmaki, A, Sipila, P, Nemoz, C, Virkkunen, P, Suortti, P |
Rok vydání: | 2011 |
Předmět: |
Nuclear and High Energy Physics
medicine.medical_specialty mammography FIS/07 - FISICA APPLICATA (A BENI CULTURALI AMBIENTALI BIOLOGIA E MEDICINA) Breast Neoplasms Radiation Dosage phase-contrast imaging 030218 nuclear medicine & medical imaging 03 medical and health sciences breast cancer 0302 clinical medicine Breast cancer medicine Humans magnetic resonance imaging Mammography Medical physics Breast Instrumentation Computed tomography laser mammography Radiation medicine.diagnostic_test business.industry Carcinoma Ductal Breast Visibility (geometry) Phase-contrast imaging Cancer computed tomography Magnetic resonance imaging medicine.disease X-ray diffraction 3. Good health Carcinoma Lobular 030220 oncology & carcinogenesis Female Histopathology Tomography X-Ray Computed X-ray optic Nuclear medicine business Synchrotrons |
Zdroj: | Journal of Synchrotron Radiation. 18:689-696 |
ISSN: | 1600-5775 0909-0495 |
Popis: | High-resolution analyser-based X-ray imaging computed tomography (HR ABI-CT) findings on in vitro human breast cancer are compared with histopathology, mammography, computed tomography (CT) and magnetic resonance imaging. The HR ABI-CT images provided significantly better low-contrast visibility compared with the standard radiological images. Fine cancer structures indistinguishable and superimposed in mammograms were seen, and could be matched with the histopathological results. The mean glandular dose was less than 1 mGy in mammography and 12-13 mGy in CT and ABI-CT. The excellent visibility of in vitro breast cancer suggests that HR ABI-CT may have a valuable role in the future as an adjunct or even alternative to current breast diagnostics, when radiation dose is further decreased, and compact synchrotron radiation sources become available. |
Databáze: | OpenAIRE |
Externí odkaz: |