Alterations of mental defeat and cognitive flexibility during cognitive behavioral therapy in patients with major depressive disorder: a single-arm pilot study

Autor: Keiko Oshiro, Tomokazu Murata, Fuminori Yamada, Remi Noguchi, Yoichi Hiramatsu, Shinobu Nagata, Eiji Shimizu, Daisuke Matsuzawa, Mari Tanaka, Takayuki Shibuya, Yoichi Seki, Mizue Yokoo, Yoshiyuki Hirano
Jazyk: angličtina
Rok vydání: 2019
Předmět:
Adult
Male
Mental defeat
Quality of life
050103 clinical psychology
medicine.medical_treatment
lcsh:Medicine
Pilot Projects
Major depressive disorder
Anxiety
Cognitive flexibility
Treatment effects
General Biochemistry
Genetics and Molecular Biology
03 medical and health sciences
Cognition
0302 clinical medicine
Quality of life (healthcare)
Surveys and Questionnaires
Intervention (counseling)
medicine
Humans
0501 psychology and cognitive sciences
In patient
030212 general & internal medicine
lcsh:Science (General)
lcsh:QH301-705.5
Depression (differential diagnoses)
Retrospective Studies
Depressive Disorder
Major
business.industry
Depression
05 social sciences
lcsh:R
General Medicine
Middle Aged
medicine.disease
Cognitive behavioral therapy
Clinical trial
Research Note
Treatment Outcome
lcsh:Biology (General)
Female
Intervention effects
business
Clinical psychology
lcsh:Q1-390
Zdroj: BMC Research Notes, Vol 12, Iss 1, Pp 1-7 (2019)
BMC Research Notes
ISSN: 1756-0500
DOI: 10.1186/s13104-019-4758-2
Popis: Objective Mental defeat affects the occurrence and chronicity of depression and cognitive flexibility. This study aimed to examine changes in mental defeat and cognitive flexibility scores after cognitive behavioral therapy including IR. In the intervention group, patients with depression (n = 18, mean age = 37.89 years) received 15 cognitive behavioral therapy sessions. Patients completed the Beck Depression Inventory-II; Mental Defeat Scale; Cognitive Flexibility Scale; EuroQol five dimensions questionnaire; Patient Health Questionnaire-9 and seven-item Generalized Anxiety Disorder Scale before the intervention, after six sessions, and post-intervention. The healthy control group (n = 33, mean age = 37.91) completed all scales once and did not receive treatment. Results Post-cognitive behavioral therapy, a significant decrease was observed in Beck Depression Inventory-II, Mental Defeat Scale, Cognitive Flexibility Scale, and Patient Health Questionnaire-9 scores. Although mental defeat and cognitive flexibility did not reach the level of the healthy control group, they demonstrated improvement. Therefore, when treating depression, mental defeat and cognitive flexibility should be measured in addition to depressive symptoms. Trial registration This study was registered retrospectively in the national UMIN Clinical Trials Registry on July 25, 2016 (registration ID: UMIN000023320)
Databáze: OpenAIRE
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