Prevalence and risk factors of dry eye disease in a British female cohort
| Autor: | Christopher J Hammond, Pirro G. Hysi, Jelle Vehof, Diana Kozareva |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2014 |
| Předmět: |
Adult
medicine.medical_specialty Aging SYMPTOMS Cross-sectional study Population SUBCOMMITTEE Cohort Studies Cellular and Molecular Neuroscience Young Adult Risk Factors Internal medicine Surveys and Questionnaires Epidemiology Prevalence Medicine Humans WORKSHOP 2007 Registries education Depression (differential diagnoses) POPULATION Aged Aged 80 and over education.field_of_study business.industry TWINSUK Pelvic pain Chronic pain ASSOCIATION Middle Aged medicine.disease DEPRESSION Sensory Systems United Kingdom Ophthalmology Cross-Sectional Studies Cohort Physical therapy Women's Health Dry Eye Syndromes Female FATTY-ACIDS medicine.symptom SENSITIVITY business Cohort study |
| Zdroj: | BRITISH JOURNAL OF OPHTHALMOLOGY, 98(12), 1712-1717. BMJ PUBLISHING GROUP |
| ISSN: | 0007-1161 |
| Popis: | To estimate the prevalence and risk factors of dry eye disease (DED) in a female cohort in the UK.Population-based cross-sectional association study of 3824 women from the TwinsUK cohort aged 20-87 years. A questionnaire was used to evaluate DED and several risk factors. Binary logistic regression, corrected for age, was used to examine the association between DED and risk factors.9.6% of women had a DED diagnosis and concomitant use of artificial tears, and 20.8% experienced DED symptoms in the past 3 months. Risk factors that were significantly associated with DED were age, asthma, eczema, the presence of any allergy, cataract surgery, rheumatoid arthritis, osteoarthritis, migraine and stroke. The highest effect sizes were found with depression, pelvic pain, irritable bowel syndrome and chronic widespread pain syndrome (all p0.0005). Subjects with DED symptoms scored significantly lower on self-perceived health, compared with controls (p=0.001).DED is common and increases with age within this cohort of female twins. We confirmed established risk factors for the first time in a British population, and found important risk factors that might relate to an underlying aetiology involving chronic pain predisposition or somatisation. |
| Databáze: | OpenAIRE |
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