Phenylethanol enhancement of preservatives used in ophthalmic preparations
| Autor: | R. M. E. Richards, R. J. McBride |
|---|---|
| Rok vydání: | 1971 |
| Předmět: |
Chlorobutanol
Preservative Pharmaceutical Science Chlorbutol Microbial Sensitivity Tests Benzoates Drug synergism Cresols Benzalkonium chloride Propyl hydroxybenzoate Chlorides Organometallic Compounds Pharmaceutic Aids medicine Pharmacology Nitrates Chlorhexidine diacetate Chromatography Ethanol Chemistry Ophthalmic preparations Drug Synergism Mercury Pseudomonas aeruginosa Ophthalmic Solutions Phenylmercuric nitrate Benzalkonium Compounds medicine.drug |
| Zdroj: | Journal of Pharmacy and Pharmacology. 23:141S-146S |
| ISSN: | 2042-7158 0022-3573 |
| DOI: | 10.1111/j.2042-7158.1971.tb08782.x |
| Popis: | The growth rates of P. aeruginosa in subinhibitory concentrations of antibacterial preservatives alone and in combination with phenylethanol were determined by an extinction method. Phenylethanol enhances the effect of benzalkonium chloride on growing cultures of P. aeruginosa and the results have been confirmed by viable counts. A similar effect is shown by phenylethanol in combination with chlorbutol, chlorhexidine diacetate, chlorocresol, merthiolate, methyl and propyl hydroxybenzoate mixture and phenylmercuric nitrate. |
| Databáze: | OpenAIRE |
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