Scalp-recorded contingent negative variation (CNV) increases during experimentally induced sustained ischemic pain in humans
| Autor: | Philipp Stude, Peter Thümler, Martin Wiemann, Alfred Lehmenkühler, Dieter Bingmann, Frank Richter, Claudia Wischniewski |
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| Rok vydání: | 2003 |
| Předmět: |
Adult
Male medicine.medical_specialty Time Factors genetic structures Ischemia Pain Contingent Negative Variation Electroencephalography Central nervous system disease Internal medicine Physical Stimulation medicine Humans Pain Measurement Brain Mapping medicine.diagnostic_test Vascular disease General Neuroscience medicine.disease eye diseases Contingent negative variation Frontal Lobe Electrophysiology Electrooculography medicine.anatomical_structure Migraine Scalp Anesthesia Cardiology Female sense organs Psychology |
| Zdroj: | Neuroscience letters. 348(1) |
| ISSN: | 0304-3940 |
| Popis: | Contingent negative variations (CNV) after acoustic stimuli (S1) followed by optical ones (S2) were recorded using electroencephalography in 22 healthy students both under control conditions and during ischemic pain to study the effects of sustained pain on CNV. Mean negative CNV-amplitudes and integrated areas below CNV were significantly larger during periods of ischemic pain than under control conditions (16.53 versus 13.11 μV, respectively (P=0.0028) and 8.318 versus 6.357 μV*s, respectively (P=0.00071)). We conclude that deep somatic pain augments CNV. Reduced CNV amplitudes occurring during migraine attacks, however, reflect other mechanisms which may mask the effects of migraine headache on CNV. |
| Databáze: | OpenAIRE |
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