The use of negative-pressure wound therapy over a cultured epithelial autograft for full-thickness wounds secondary to purpura fulminans in an infant
| Autor: | Alvin Wen Choong Chua, Gavin Chun-Wui Kang, Benjamin Kah Liang Goh, Savitha Ramachandran, Bien-Keem Tan, Li-Wei Chiang, Khong Yik Chew |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
Wound therapy RD1-811 medicine.medical_treatment Case Report 030207 dermatology & venereal diseases 03 medical and health sciences 0302 clinical medicine Negative-pressure wound therapy medicine Autografts Child Epithelium cells Skin Anterior abdomen integumentary system business.industry 030208 emergency & critical care medicine Research/Experimental medicine.disease Surgery Severe morbidity Full thickness business Total body surface area Pediatric population Purpura fulminans |
| Zdroj: | Archives of Plastic Surgery Archives of Plastic Surgery, Vol 48, Iss 3, Pp 338-343 (2021) |
| ISSN: | 2234-6171 2234-6163 |
| Popis: | Purpura fulminans is a serious condition that can result in severe morbidity in the pediatric population. Although autologous skin grafts remain the gold standard for the coverage of partial- to full-thickness wounds, they have several limitations in pediatric patients, including the lack of planar donor sites, the risk of hemodynamic instability, and the limited graft thickness. In Singapore, an in-house skin culture laboratory has been available since 2005 for the use of cultured epithelial autografts (CEAs), especially in burn wounds. However, due to the fragility of CEAs, negative-pressure wound therapy (NPWT) dressings have been rarely used with CEAs. With several modifications, we report a successful case of NPWT applied over a CEA in an infant who sustained 30% total body surface area full-thickness wounds over the anterior abdomen, flank, and upper thigh secondary to purpura fulminans. We also describe the advantages of using NPWT dressing over a CEA, particularly in pediatric patients. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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