Bisnortriterpenes from Salacia madagascariensis

Autor:	Babu L. Tekwani, Shabana I. Khan, Deborah A Thiem, Albert T Sneden
Rok vydání:	2005
Předmět:	Stereochemistry Pharmaceutical Science Microbial Sensitivity Tests Pharmacognosy Plant Roots Tanzania Analytical Chemistry Salacia Celastraceae chemistry.chemical_compound Triterpene Drug Discovery Animals Petroleum ether Nuclear Magnetic Resonance Biomolecular Pharmacology chemistry.chemical_classification Leishmania Plants Medicinal biology Molecular Structure Organic Chemistry biology.organism_classification Quinone methide Terpenoid Triterpenes Complementary and alternative medicine chemistry Molecular Medicine
Zdroj:	Journal of natural products. 68(2)
ISSN:	0163-3864
Popis:	A new bisnortriterpene quinone methide, 20-epi-isoiguesterinol (2), and a new 6-oxophenolic triterpene, 6-oxoisoiguesterin (5), as well as two known compounds, isoiguesterin (1) and isoiguesterinol (4), were isolated from the petroleum ether extract of the roots of Salacia madagascariensis. Isoiguesterin (1) and 20-epi-isoiguesterinol (2) showed potent activity against Leishmania.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f458bc2341b8d528a7816d1143ace5b https://pubmed.ncbi.nlm.nih.gov/15730255 Zobrazit plný text záznamu