One-Year Follow-Up of Conduction Abnormalities After Transcatheter Aortic Valve Implantation With the SAPIEN 3 Valve
| Autor: | Nina Ajmone Marsan, Jeroen J. Bax, E. Mara Vollema, Victoria Delgado, Giulia Dolci, Arend de Weger, Frank van der Kley |
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| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
Male
medicine.medical_specialty Time Factors 030204 cardiovascular system & hematology Paced Rhythm Transcatheter Aortic Valve Replacement 03 medical and health sciences QRS complex Electrocardiography 0302 clinical medicine Postoperative Complications Cardiac Conduction System Disease Heart Conduction System Internal medicine medicine Humans 030212 general & internal medicine Netherlands Retrospective Studies Aged 80 and over medicine.diagnostic_test Left bundle branch block business.industry Incidence Cardiac Pacing Artificial Retrospective cohort study Aortic Valve Stenosis Right bundle branch block medicine.disease Prognosis Stenosis Echocardiography Cardiology Female Cardiology and Cardiovascular Medicine business Atrioventricular block Follow-Up Studies |
| Zdroj: | American Journal of Cardiology, 124(8), 1239-1245. EXCERPTA MEDICA INC-ELSEVIER SCIENCE INC |
| Popis: | Long-term evolution of new-onset conduction abnormalities and need of permanent pacemaker implantation (PPI) after transcatheter aortic valve implantation (TAVI) have not been extensively evaluated. We describe the incidence and time course of new conduction abnormalities and the rate of PPI with the new-generation transcatheter aortic valve prosthesis Edwards SAPIEN 3 (S3). In total, 266 patients with severe aortic stenosis who underwent TAVI were retrospectively analyzed. Twelve-lead electrocardiograms at base-line, after TAVI, at discharge, at 1-, 6-, and 12-month follow-up were evaluated to identify conduction abnormalities and PPI requirements to investigate the correlates of PPI. After TAVI, a significant increase in PR interval duration and in QRS complex width was observed. New-onset left bundle branch block was observed in 65 patients (24 %) after TAVI. The number of patients with left bundle branch block was maximum at hospital discharge and decreased at 12-month follow-up (39% and 32%, respectively). Thirty-five patients (13%) required PPI during the follow-up. However, paced rhythm was only observed in 7% of the patients with a complete 12-month follow-up. Patients who underwent PPI had a higher prevalence of first-degree atrioventricular block, complete right bundle branch block, and wider QRS complex at baseline. Baseline right bundle branch block and QRS width immediately after TAVI were the only variables independently associated with PPI. In conclusion, conduction disorders have a temporary nature after TAVI and showed a trend toward stabilization during the following months. With this new-generation device, the incidence of new conduction abnormalities requiring PPI is relatively low. (C) 2019 The Author(s). Published by Elsevier Inc. |
| Databáze: | OpenAIRE |
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