Elizabethkingia miricolainfection in Chinese spiny frog (Quasipaa spinosa)
| Autor: | Kaiyu Wang, Zi Jun Zhong, Ze Xiao Yang, Wei Min Lai, Ping Ouyang, Xiao Li Huang, De Fang Chen, Geng Yi, Chao Huang, Chang Liang Huo, Xue Ping Lei |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
Florfenicol
China Ranidae 040301 veterinary sciences Elizabethkingia miricola Spleen Microbial Sensitivity Tests Kidney Microbiology 0403 veterinary science 03 medical and health sciences chemistry.chemical_compound Flavobacteriaceae Infections RNA Ribosomal 16S medicine Animals Humans Quasipaa spinosa 030304 developmental biology Chryseobacterium Thiamphenicol 0303 health sciences General Veterinary General Immunology and Microbiology biology Outbreak 04 agricultural and veterinary sciences General Medicine 16S ribosomal RNA biology.organism_classification Anti-Bacterial Agents medicine.anatomical_structure Liver chemistry DNA Gyrase Infectious disease (medical specialty) Sequence Analysis |
| Zdroj: | Transboundary and Emerging Diseases. 66:1049-1053 |
| ISSN: | 1865-1682 1865-1674 |
| DOI: | 10.1111/tbed.13101 |
| Popis: | Elizabethkingia miricola is a Gram-negative rod which has been incriminated in severe infections in humans. Recently, a serious infectious disease was identified in Chinese spiny frogs (Quasipaa spinosa), in the Sichuan Province of China; the disease was characterized by corneal opacity, the presence of ascites and neurological symptoms. A Gram-negative bacillus was isolated from the liver, spleen and kidney of the diseased frogs. Experimental infection test revealed that the bacillus could infect the frogs Q. spinosa and the LD50 value was 1.19 × 106 cfu per frog. The isolated Gram-negative bacillus was identified as E. miricola according to phenotypic characteristics, 16S rRNA and gyrB gene sequence analysis. The isolated strain was only susceptible to florfenicol among all investigated chemotherapeutic agents. Histological examination revealed that E. miricola infection caused pathological lesions to multiple organs and tissues, especially in the liver, brain, kidney. These results confirmed that E. miricola is an emerging pathogen of Chinese spiny frogs. |
| Databáze: | OpenAIRE |
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