Natural immunity in conventionally and organically reared turkeys and its relation with antimicrobial resistance
| Autor: | Mughini-Gras, Lapo, Di Martino, Guido, Moscati, Livia, Buniolo, Filippo, Cibin, Veronica, Bonfanti, Lebana, IRAS OH Epidemiology Microbial Agents, dIRAS RA-I&I I&I |
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| Přispěvatelé: | IRAS OH Epidemiology Microbial Agents, dIRAS RA-I&I I&I |
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
Male
Veterinary medicine Turkeys Turkey Tetracycline Drug Resistance Microbial Sensitivity Tests Biology 03 medical and health sciences Antibiotic resistance organic farming Ampicillin Drug Resistance Bacterial medicine Escherichia coli intensive farming Innate Animals antimicrobial resistance Animal Husbandry Escherichia coli Infections 030304 developmental biology lcsh:SF1-1100 Escherichia coli Infections/drug therapy Microbial Sensitivity Tests/veterinary 0303 health sciences Organic Agriculture Escherichia coli/drug effects Sulfamethoxazole Bacterial Immunity 0402 animal and dairy science 04 agricultural and veterinary sciences General Medicine Immunology Health and Disease Antimicrobial 040201 dairy & animal science Trimethoprim Immunity Innate Ciprofloxacin natural immunity Italy Streptomycin Animal Science and Zoology Female lcsh:Animal culture Animal Husbandry/methods medicine.drug |
| Zdroj: | Poultry Science, Vol 99, Iss 2, Pp 763-771 (2020) Poultry Science Poultry Science, 99(2), 763. Poultry Science Association |
| ISSN: | 0032-5791 |
| Popis: | Suboptimal animal welfare may affect natural immunity, rendering animals more susceptible to environmentally conditioned diseases, including those requiring antimicrobial treatment, which may promote antimicrobial resistance (AMR) in bacterial populations. Herewith, we tested the hypothesis that conventionally raised turkeys have higher levels of AMR in indicator Escherichia coli bacteria, but lower levels of natural immunity, as compared to turkeys reared under organic conditions. Litter and serum samples were collected from 28 conventional and 4 organic turkey farms: E. coli isolates from litter were tested for resistance to 14 antimicrobials, while 3 parameters of natural immunity (i.e., lysozyme, hemolytic complement levels, and serum bactericidal activity) were assessed in the sera. Resistant E. coli isolates were identified in both conventional and organic farms but generally more frequently in conventional farms. High rates of resistance to ampicillin (96%), tetracycline (95%), streptomycin (82%), sulfamethoxazole (80%), ciprofloxacin (73%), and trimethoprim (71%), as well as high rates of multiresistance, were observed in conventional farms. Organically raised turkeys had significantly higher levels of lysozyme and serum bactericidal activity than conventional turkeys, and these levels were also higher in turkeys housed in farms where AMR frequency was lower. Findings support the hypothesis that conventional farming conditions may affect turkeys' natural immunity, rendering the animals more susceptible to environmentally conditioned diseases requiring antimicrobial treatment, which would in turn promote AMR. Reducing AMR in turkey farming is therefore more likely to be successful when considering animal welfare as an option to reduce the need of antimicrobial use. |
| Databáze: | OpenAIRE |
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