| Autor: |
Lixin Rui, Christian M. Capitini, Thomas A. Waldmann, Madelyn Chen, Samantha Bebel, Apoorv Kondapelli, Alexander Rosiejka, Yangguang Li, Yunxia Liu, Amanda Kelm, David T. Yang, Shanxiang Zhang, Anusara Daenthanasanmak, Paul D. Bates, Fen Zhu, Nguyet M. Hoang, Li Lu, Shuichi Kimpara |
| Rok vydání: |
2023 |
| Popis: |
Supplementary Methods, Supplementary Figures and Figure Legends. Figure S1. EGR1 is a downstream target of BCR and JAK1 signaling (related to Figure 1). Figure S2. Sensitivity of MCL cell lines to EGR1 shRNAs and statistical analysis (related to Figure 2). Figure S3. EGR1 motif analysis and gene set enrichment analysis of RNA-seq data (related to Figure 3). Figure S4. Enrichment of E2F pathway genes in ABC DLBCL after EGR1 knockdown (related to Figure 4). Figure S5. EGR1 regulates expression of MYC and MYC targets and OCI-Ly10 xenografts (related to Figure 4). Figure S6. Enrichment of EGR1 on EGR1 own promoter and EP300 regulatory (5'UTR and enhancer) regions (related to Figure 4). Figure S7. Inhibition of EGR1 transcription and tumor growth by mithramycin (related to Figure 4). Figure S8. Synergism of mithramycin and lenalidomide in ABC DLBCL (related to Figure 6). Figure S9. Expression of MYC and MYC target genes is higher in ABC DLBCL than GCB DLBCL patient samples (related to the Discussion). Figure S10. No correlation between EGR1 and MYC expression in DLBCL cell lines and patient samples (related to the Discussion). |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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