Impedance Analysis of Colloidal Gold Nanoparticles in Chromatography Paper for Quantitation of an Immunochromatographic Assay
| Autor: | Fumitaka Hori, Tatsumi Kuretake, Shigeyasu Uno, Yuji Harada |
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| Rok vydání: | 2016 |
| Předmět: |
Chromatography
Paper Nanoparticle Metal Nanoparticles 02 engineering and technology 010402 general chemistry 01 natural sciences Chromatography Affinity Analytical Chemistry Electric Impedance Colloids Particle Size Electrical impedance Reagent Strips Detection limit Strip test Chromatography Reagent strip Chemistry Equipment Design 021001 nanoscience & nanotechnology 0104 chemical sciences Paper chromatography Colloidal gold Particle size Gold 0210 nano-technology |
| Zdroj: | Analytical sciences : the international journal of the Japan Society for Analytical Chemistry. 32(3) |
| ISSN: | 1348-2246 |
| Popis: | A detection method of gold nanoparticles in chromatography paper has been developed for a simple, cost-effective and reliable quantitation of immunochromatographic strip test. The time courses of the solution resistance in chromatography paper with the gold nanoparticles solution are electrochemically measured by chrono-impedimetry. The dependence of the solution resistance on the concentration of gold nanoparticles has been successfully observed. The main factor to increase the solution resistance may be obstruction of the ion transport due to the presence of gold nanoparticles. The existence of gold nanoparticles with 1.92 × 10(9) particles/mL in an indistinctly-colored chromatography paper is also identified by a solution resistance measurement. This indicates that the solution resistance assay has the potential to lower the detection limit of the conventional qualitative assay. |
| Databáze: | OpenAIRE |
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