Dietary isohumulones, the bitter components of beer, raise plasma HDL-cholesterol levels and reduce liver cholesterol and triacylglycerol contents similar to PPARalpha activations in C57BL/6 mice

Autor:	Chiaki Oyamada, Keiji Kondo, Hideharu Odai, Mayu Hosono, Yutaka Miura, Shinichi Oikawa
Rok vydání:	2005
Předmět:	Hydroxymethylglutaryl-CoA Synthase medicine.medical_specialty Arteriosclerosis Medicine (miscellaneous) Gene Expression Cyclopentanes Biology chemistry.chemical_compound Mice Internal medicine Blood plasma Coenzyme A Ligases medicine Animals PPAR alpha RNA Messenger Triglycerides chemistry.chemical_classification Lipoprotein lipase Nutrition and Dietetics Fenofibrate Dose-Response Relationship Drug Cholesterol Cholesterol HDL Fatty acid Beer Membrane Transport Proteins Lipid metabolism Metabolism Fatty Acid Transport Proteins Dietary Fats Mice Inbred C57BL Dose–response relationship Lipoprotein Lipase Endocrinology chemistry Liver lipids (amino acids peptides and proteins) Female Acyl-CoA Oxidase medicine.drug
Zdroj:	The British journal of nutrition. 93(4)
ISSN:	0007-1145
Popis:	The effects of dietary isohumulones, the main components accounting for the bitter taste of beer, on lipid metabolism were examined. Young female C57BL/6N mice were fed diets containing isomerized hop extract (IHE), which consists mainly of isohumulones. Administration of IHE with an atherogenic (high-fat and high-cholesterol) diet for 2 weeks resulted in a significant increase in plasma HDL-cholesterol (PPP
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f2cd6b9a16d19166265f4c10b170d40 https://pubmed.ncbi.nlm.nih.gov/15946420 Zobrazit plný text záznamu