Genetic and epigenetic characterization of hypodiploid acute lymphoblastic leukemia
| Autor: | Anders Castor, Andrea Biloglav, Johnbosco Tayebwa, Kajsa Paulsson, Setareh Safavi, Srinivas Veerla, Mikael Behrendtz, Bertil Johansson, Markus Hansson, Linda Olsson, Molly Blendberg |
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| Rok vydání: | 2015 |
| Předmět: |
Adult
Male medicine.medical_specialty chromosomal instability Adolescent hypodiploidy Cell- och molekylärbiologi DNA Mutational Analysis Abnormal Karyotype Aneuploidy acute lymphoblastic leukemia Biology Polymorphism Single Nucleotide DNA sequencing Epigenesis Genetic Internal medicine Chromosome instability medicine Humans Child In Situ Hybridization Fluorescence Exome sequencing Aged next generation sequencing Genetics Hematology Reverse Transcriptase Polymerase Chain Reaction Infant Middle Aged Precursor Cell Lymphoblastic Leukemia-Lymphoma medicine.disease Gene Expression Regulation Neoplastic Oncology Child Preschool Medical genetics Hypodiploidy Female Transcriptome Cell and Molecular Biology Research Paper Hypodiploid Acute Lymphoblastic Leukemia |
| Zdroj: | Oncotarget |
| ISSN: | 1949-2553 |
| DOI: | 10.18632/oncotarget.6000 |
| Popis: | // Setareh Safavi 1 , Linda Olsson 1, 2 , Andrea Biloglav 1 , Srinivas Veerla 3 , Molly Blendberg 1 , Johnbosco Tayebwa 1 , Mikael Behrendtz 4 , Anders Castor 5 , Markus Hansson 6 , Bertil Johansson 1, 2 , Kajsa Paulsson 1 1 Division of Clinical Genetics, Department of Laboratory Medicine, Lund University, Lund, Sweden 2 Department of Clinical Genetics, University and Regional Laboratories, Region Skane, Lund, Sweden 3 Division of Oncology and Pathology, Department of Clinical Sciences Lund, Lund University, Lund, Sweden 4 Department of Pediatrics, Linkoping University Hospital, Linkoping, Sweden 5 Department of Pediatrics, Skane University Hospital, Lund University, Lund, Sweden 6 Division of Hematology, Skane University Hospital, Lund University, Lund, Sweden Correspondence to: Setareh Safavi, e-mail: setareh.safavi@med.lu.se Kajsa Paulsson, e-mail: kajsa.paulsson@med.lu.se Keywords: acute lymphoblastic leukemia, hypodiploidy, next generation sequencing, chromosomal instability Received: August 26, 2015 Accepted: October 17, 2015 Published: October 30, 2015 ABSTRACT Purpose: To investigate the genetic and epigenetic landscape of hypodiploid ( |
| Databáze: | OpenAIRE |
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