Ionic Functionalization of Hydrophobic Colloidal Nanoparticles To Form Ionic Nanoparticles with Enzymelike Properties
| Autor: | Yanyue Wang, Cuichen Wu, Weijia Hou, Weihong Tan, Sena Cansiz, Daniel L. Purich, Shengyuan Yang, Yuan Liu, Liqin Zhang, Tao Chen, Yuan Wu, Cheng Cui |
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| Rok vydání: | 2015 |
| Předmět: |
inorganic chemicals
Inorganic chemistry Ionic bonding Nanoparticle 02 engineering and technology 010402 general chemistry Electron 01 natural sciences Biochemistry Article Catalysis Colloid Colloid and Surface Chemistry Microscopy Electron Transmission Pulmonary surfactant mental disorders Transmission Colloids Solubility Ions Microscopy Chemistry Spectrum Analysis technology industry and agriculture Aqueous two-phase system Substrate (chemistry) Metabolic Disorders Radboud Institute for Molecular Life Sciences [Radboudumc 6] General Chemistry 021001 nanoscience & nanotechnology Enzymes 0104 chemical sciences Chemical engineering Chemical Sciences Nanoparticles Surface modification 0210 nano-technology Hydrophobic and Hydrophilic Interactions |
| Zdroj: | Journal of the American Chemical Society, 137, 47, pp. 14952-8 Journal of the American Chemical Society Journal of the American Chemical Society, 137, 14952-8 Journal of the American Chemical Society, vol 137, iss 47 |
| ISSN: | 1520-5126 0002-7863 |
| DOI: | 10.1021/jacs.5b08533 |
| Popis: | Item does not contain fulltext Inorganic colloidal nanoparticles (NPs) stabilized by a layer of hydrophobic surfactant on their surfaces have poor solubility in the aqueous phase, thus limiting their application as biosensors under physiological conditions. Here we report a simple model to ionize various types of hydrophobic colloidal NPs, including FePt, cubic Fe3O4, Pd, CdSe, and NaYF4 (Yb 30%, Er 2%, Nd 1%) NPs, to multicharged (positive and negative) NPs via ligand exchange. Surfaces of neutral hydrophobic NPs were converted to multicharged ions, thus making them soluble in water. Furthermore, peroxidase-like activity was observed for ionic FePt, Fe3O4, Pd, and CdSe NPs, of which FePt and CdSe catalyzed the oxidation of the colorless substrate 3,3',5,5'-tetramethylbenzidine (TMB) to the blue-colored product in the absence of H2O2, while Pd and Fe3O4 catalyzed the oxidization of TMB in the presence of H2O2. With the benefit of the ionic functionalization protocols described herein, colloidal NPs should gain wider use as biomarkers, nanozymes, and biosensors. |
| Databáze: | OpenAIRE |
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