Atrial fibrillation and COVID-19 in older patients: a complex, dangerous, association. An analysis of the GeroCovid Registry
| Autor: | R. Antonelli Incalzi, G. Pelagalli, Giuseppe Bellelli, Pietro Gareri, Caterina Trevisan, Fabio Monzani, Gianluca Zia, Alba Malara, Stefano Volpato, Alessandra Coin, Stefano Fumagalli, S Del Signore, Enrico Mossello |
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| Přispěvatelé: | Fumagalli, S, Pelagalli, G, Trevisan, C, Del Signore, S, Volpato, S, Gareri, P, Mossello, E, Malara, A, Monzani, F, Coin, A, Bellelli, G, Zia, G, Antonelli Incalzi, R |
| Rok vydání: | 2021 |
| Předmět: |
Geriatrics
medicine.medical_specialty education.field_of_study Atrial Fibrillation (AF) - Prevalence and Incidence of Atrial Fibrillation business.industry Population Atrial fibrillation medicine.disease Comorbidity atrial fibrillation COVID older Physiology (medical) Internal medicine Heart failure Cohort CHA2DS2–VASc score medicine Atrial fibrillation COVID-19 Older Patients AcademicSubjects/MED00200 Cardiology and Cardiovascular Medicine business education Stroke |
| Zdroj: | Europe PubMed Central Europace |
| ISSN: | 1532-2092 1099-5129 |
| DOI: | 10.1093/europace/euab116.154 |
| Popis: | Funding Acknowledgements Type of funding sources: None. OnBehalf the GeroCovid Investigators Introduction. Atrial fibrillation (AF) is the most frequent arrhythmia diagnosed in elderly patients. It often associates with disabling complications, such as stroke and systemic embolism. COVID-19 severely affects older subjects, who show a particularly high mortality, often related to relevant alterations in coagulation and inflammation cascade. Purpose. Aim of this study was to evaluate how the presence of a prevalent form of AF (at admission or in clinical history) influenced the clinical course of COVID-19 in an aged in-hospital population. Methods. We studied the acute patients included in GeroCovid, a multicenter retrospective-prospective registry designed by the Italian Society of Gerontology and Geriatric Medicine and the Norwegian Geriatrics Society. GeroCovid, independently of the healthcare setting and without exclusion criteria, enrolled subjects aged >60 years to analyze risk factors, signs, symptoms and outcomes of COVID-19 in older people. For the purpose of this study, only the acute, in-hospital, cohort was evaluated. Results. Between March 1st and June 6th 2020, 2474 patients were enrolled in GeroCovid. Of these, 806 (32.6%) were assisted in hospital, for an acute condition (age: 79 ± 9 years; men: 51.7%). The prevalence of AF was 21.8%. Patients with the arrhythmia were older (82 ± 8 vs. 77 ± 9 years; p Conclusions. AF is frequently observed in older patients with COVID-19. Subjects with both conditions have a more complex clinical status and show a higher in-hospital mortality, thus requesting a particularly careful and intensive management. |
| Databáze: | OpenAIRE |
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