Serosurvey of arthropod-borne diseases among shelter dogs in the Cumberland Gap Region of the United States

Autor: Vina Faulkner, Daniel Kish, Karen Gruszynski, Michele Coarsey, Dawn Spangler, Gilbert Patterson, Ashutosh Verma, Hemant Naikare, Matthew Tanhauser, Charles T. Faulkner, Paul Schmidt
Rok vydání: 2020
Předmět:
Male
Anaplasmosis
Canine heartworm
Rocky Mountain spotted fever
Rickettsia rickettsii
0403 veterinary science
0302 clinical medicine
Lyme disease
Seroepidemiologic Studies
Dog Diseases
Rocky Mountain Spotted Fever
Appalachian Region
lcsh:Veterinary medicine
biology
Coinfection
04 agricultural and veterinary sciences
General Medicine
Antibodies
Bacterial
Canis
Ehrlichiosis (canine)
Female
Dirofilariasis
Gap region
Research Article
Anaplasma
040301 veterinary sciences
Ehrlichia canis
Dirofilaria immitis
Shelter animals
030231 tropical medicine
Ehrlichia
Vector Borne Diseases
Rocky Mountain spotted fever (RMSF)
03 medical and health sciences
Dogs
parasitic diseases
medicine
Animals
Cumberland
Borrelia burgdorferi
General Veterinary
Ehrlichiosis
bacterial infections and mycoses
biology.organism_classification
medicine.disease
Anaplasma phagocytophilum
Virology
Antigens
Helminth
lcsh:SF600-1100
Zdroj: BMC Veterinary Research, Vol 16, Iss 1, Pp 1-7 (2020)
BMC Veterinary Research
ISSN: 1746-6148
DOI: 10.1186/s12917-020-02440-1
Popis: Background The Cumberland Gap Region (CGR) of the United States is a natural corridor between the southeastern, northeastern, and midwestern regions of the country. CGR has also many species of ticks and mosquitos that serve as competent vectors for important animal and human pathogens. In this study, we tested dogs from six different animal shelters in the CGR for Rocky Mountain spotted fever (RMSF), anaplasmosis, Lyme disease, canine ehrlichiosis and canine heartworm disease. Results Sera from 157 shelter dogs were tested for antibodies to RMSF agent, Rickettsia rickettsii, using an indirect immunofluorescence assay. Sixty-six dogs (42.0%) were positive for either IgM or IgG, or both IgM and IgG antibodies to R. rickettsii. Moreover, the same set of sera (n = 157) plus an and additional sera (n = 75) from resident dogs at the same shelters were tested using the SNAP 4Dx Plus. Of 232 dogs tested, two (0.9%) were positive for antibodies to Anaplasma phagocytophilum/A. platys, nine (3.9%) were positive for antibodies to Borrelia burgdorferi, 23 (9.9%) for positive for antibodies to Ehrlichia canis/E. ewingii, and 13 (5.6%) were positive for Dirofilaria immitis antigen. Co-infection with two or more etiologic agents was detected in five animals. Three dogs had antibodies to both B. burgdorferi and E. canis/E. ewingii, and two dogs were positive for D. immitis antigen and antibodies to B. burgdorferi and E. canis/E. ewingii. Conclusions Shelter dogs in the CGR are exposed to a number of important vector-borne pathogens. Further studies are required to ascertain the roles these animals play in maintenance and transmission of these pathogens.
Databáze: OpenAIRE
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