A recombinant infectious bronchitis virus from a chicken with a spike gene closely related to that of a turkey coronavirus
Autor: | Eric Delwart, Shixing Yang, Yu Ling, Xu Chen, Luying Sun, Yan Wang, Chuang Li, Yu Li, Qianben Song, Wen Zhang, Xuejiao Cui, Su Zhu, Xutao Deng |
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Rok vydání: | 2020 |
Předmět: |
Turkeys
Viral metagenomics animal structures Infectious bronchitis virus Genome Viral Biology medicine.disease_cause Genome recombination law.invention 03 medical and health sciences law Virology medicine Animals Gene Phylogeny 030304 developmental biology Coronavirus Recombination Genetic Whole genome sequencing 0303 health sciences Phylogenetic tree 030306 microbiology Brief Report General Medicine Turkey coronavirus Spike Glycoprotein Coronavirus embryonic structures Recombinant DNA Metagenomics Chickens |
Zdroj: | Archives of Virology |
ISSN: | 1432-8798 0304-8608 |
Popis: | Using viral metagenomics, the complete genome sequence of an infectious bronchitis virus (IBV) strain (named ahysx-1) from a fecal sample from a healthy chicken in Anhui province, China, was determined. The genome sequence of ahysx-1 was found to be very similar to that of IBV strain ck/CH/LLN/131040 (KX252787), except for the spike gene region, which is similar to that of a turkey coronavirus strain (EU022526), suggesting that ahysx-1 is a recombinant. Recombination analysis and phylogenetic analysis based on the genomic sequences of ahysx-1 and other related strains confirmed that ahysx-1 appears to be a recombinant resulting from a recombination event that occurred between a chicken coronavirus and a turkey coronavirus. Further studies need to be performed to determine whether this recombinant IBV strain is pathogenic and whether it is transmitted between chickens and turkeys. Electronic supplementary material The online version of this article (10.1007/s00705-019-04488-3) contains supplementary material, which is available to authorized users. |
Databáze: | OpenAIRE |
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