A comparison between 2- and 3-dimensional approaches to solid component measurement as radiological criteria for sublobar resection in lung adenocarcinoma ≤ 2 cm in size
| Autor: | Toki Saito, Jun-ichi Nitadori, Yukihiro Yoshida, Jiro Sato, Toshiki Manaka, Yoshikazu Nakajima, Takehito Doke, Jun Nakajima, Tempei Miyaji, Takuhiro Yamaguchi, Aya Shinozaki-Ushiku, Hiroshi Oyama, Masashi Fukayama |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
Adult
Male Lung Neoplasms Adenocarcinoma 03 medical and health sciences 0302 clinical medicine Imaging Three-Dimensional Medicine Humans Maximum size In patient Glycosides Pneumonectomy Aged Neoplasm Staging 3d measurement Aged 80 and over Lung business.industry General Medicine Middle Aged medicine.disease Pregnanes Sublobar resection Solid component Survival Rate medicine.anatomical_structure 030220 oncology & carcinogenesis Radiological weapon 030211 gastroenterology & hepatology Surgery Female business Nuclear medicine Tomography X-Ray Computed |
| Zdroj: | Surgery today. 49(10) |
| ISSN: | 1436-2813 |
| Popis: | We compared three-dimensional (3D) and two-dimensional (2D) measurements of the solid component to determine radiological criteria for sublobar resection of lung adenocarcinoma ≤ 2 cm in size. We included 233 surgical cases. The maximum size of the solid component for 3D measurement was calculated by delineating the solid component on successive axial images and reconstructing the 3D surface model. The predictive performance for adenocarcinoma in situ (n = 43) and minimally invasive adenocarcinoma (n = 77) were equivalent to areas under the curve of 0.871 and 0.857 for 2D and 3D measurements (p = 0.229), respectively. A solid component of 5 mm had a prognostic impact on both measurements ( ≤ 5 mm versus > 5 mm; p = 0.003 for 2D and p = 0.002 for 3D, log-rank test). Survival rates at 5 years were 94.7–96.9% following lobectomy and sublobar resection among patients with a solid component ≤ 5 mm in size. Sublobar resection resulted in worse survival rates, with declines at 5 years of 15.8% on 2D and 11.5% on 3D measurements, than lobectomy in patients with a solid component > 5 mm in size. A solid component ≤ 5 mm in size is an appropriate criterion for sublobar resection for both measurements. In addition, 2D measurement is justified because of its simple implementation. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full text from SpringerLink