Pregnancy Outcome at Extremely Advanced Maternal Age

Autor: Nir Melamed, Kinneret Tenenbaum-Gavish, Gadi Ben-Shitrit, Ron Bardin, Avi Ben-Haroush, Yariv Yogev
Rok vydání: 2011
Předmět:
Zdroj: Obstetric Anesthesia Digest. 31:156-157
ISSN: 0275-665X
DOI: 10.1097/01.aoa.0000400299.33571.23
Popis: The purpose of this study was to evaluate pregnancy outcome in women at extremely advanced maternal age (≥ 45 years).We compared the condition of women aged ≥ 45 years (n = 177) in a 10:1 ratio (20-29, 30-39, and 40-44 years.). Subgroup analysis compared the condition of women aged 45-49 years with those women aged ≥ 50 years.The rates of gestational diabetes mellitus and hypertensive complications were higher for the study group, compared with the whole group (17.0% vs 5.6% and 19.7% vs 4.5%, respectively; P.001), as was the rate of preterm delivery at37 and34 weeks of gestation (odds ratio [OR], 2.1; 95% confidence interval [CI], 1.2-3.6 and OR, 3.5; 95% CI, 1.4-9.0, respectively). The rates of cesarean delivery (OR, 31.8; 95% CI, 18.0-56.1), placenta previa, postpartum hemorrhage, and adverse neonatal outcome were significantly higher among the study group. The risk for gestational diabetes mellitus, preeclampsia toxemia, preterm delivery, and neonatal intensive care unit admission was increased for women aged ≥ 50 years.Pregnancy at extreme advanced maternal age is associated with increased maternal and fetal risk.
Databáze: OpenAIRE