Hyaluronic acid/serotonin-decorated cerium dioxide nanomedicine for targeted treatment of ulcerative colitis

Autor:	Yanyao Gao, Jing Zou, Bo Chen, Yuhao Cao, Datao Hu, Yuchen Zhang, Xinxin Zhao, Jinpeng Wen, Kailai Liu, Ke Wang
Rok vydání:	2023
Předmět:	Biomedical Engineering General Materials Science
Zdroj:	Biomaterials Science. 11:618-629
ISSN:	2047-4849 2047-4830
Popis:	Ulcerative colitis (UC) is a chronic nonspecific inflammatory bowel disease often characterized by rapid progression and frequent comorbidities that make its treatment challenging. In colonic ulcers of UC patients, myeloperoxidase (MPO) is highly expressed, which results in an abundance of macrophages and reactive oxygen species. This study developed an active MPO-targeting hyaluronic acid/serotonin ceria nanoenzyme (HA-5-HT@CeO
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f04cd5fb4ee2c221a1886a7e29ec71c https://doi.org/10.1039/d2bm01256a Zobrazit plný text záznamu