Burkitt Lymphoma Preceded by Autoimmune Hemolytic Anemia due to Anti-D Antibody
| Autor: | Yoshiaki Chinen, Shotaro Tatekawa, Tomoko Takimoto, Shigeo Horiike, Yayoi Matsumura-Kimoto, Junya Kuroda, Tsutomu Kobayashi, Masafumi Taniwaki, Saori Maegawa, Taku Tsukamoto, Kazuna Tanba, Mio Yamamoto-Sugitani, Hisao Nagoshi, Yosuke Matsumoto, Yukari Sumida, Shinsuke Mizutani, Yuji Shimura, Yoshimi Mizuno |
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| Rok vydání: | 2016 |
| Předmět: |
Anemia
Prednisolone Rho(D) Immune Globulin 030204 cardiovascular system & hematology 03 medical and health sciences 0302 clinical medicine Antigen Internal Medicine medicine Humans Aged biology business.industry Autoantibody General Medicine medicine.disease Burkitt Lymphoma Lymphoma 030220 oncology & carcinogenesis Immunology biology.protein Female Rituximab Anemia Hemolytic Autoimmune Autoimmune hemolytic anemia Antibody business medicine.drug |
| Zdroj: | Internal Medicine. 55:2253-2258 |
| ISSN: | 1349-7235 0918-2918 |
| Popis: | We herein report a rare case of Burkitt lymphoma (BL) preceded by autoimmune hemolytic anemia (AIHA) caused by autoantibodies against D antigen. After a partial response to AIHA with prednisolone (PSL) treatment for 7 months, the patient developed BL with a t(8;22)(q24;q11.2) chromosomal translocation. Intensive immunochemotherapy, including rituximab, led to a complete response (CR) of BL; however, anti-D antibody remained detectable in the plasma and antibody-dissociated solution from erythrocytes, thus continuous therapy with PSL was necessary even after achievement of the CR. BL with AIHA is extremely rare, with only one previously reported case in the literature. |
| Databáze: | OpenAIRE |
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