The first evidence of deinoxanthin from Deinococcus sp. Y35 with strong algicidal effect on the toxic dinoflagellate Alexandrium tamarense
| Autor: | Xueqian Lei, Chengwei Guan, Huajun Zhang, Yi Li, Yun Tian, Zhangran Chen, Hong Xu, Zhiming Yu, Hong Zhu, Tianling Zheng, Wei Zheng |
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| Rok vydání: | 2015 |
| Předmět: |
chemistry.chemical_classification
Reactive oxygen species Magnetic Resonance Spectroscopy Environmental Engineering biology Harmful Algal Bloom Health Toxicology and Mutagenesis Dinoflagellate biology.organism_classification Carotenoids Pollution Algal bloom Mass Spectrometry Microbiology Chloroplast chemistry Alexandrium tamarense Dinoflagellida Environmental Chemistry Deinococcus Reactive Oxygen Species Waste Management and Disposal Bacteria EC50 |
| Zdroj: | Journal of Hazardous Materials. 290:87-95 |
| ISSN: | 0304-3894 |
| DOI: | 10.1016/j.jhazmat.2015.02.070 |
| Popis: | Harmful algal blooms (HABs) could be deemed hazardous materials in aquatic environment. Alexandrium tamarense is a toxic HAB causing alga, which causes serious economic losses and health problems. In this study, the bacterium Deinococcus xianganeasis Y35 produced a new algicide, showing a high algicidal effect on A. tamarense. The algicidal compound was identified as deinoxanthin, a red pigment, based on high resolution mass spectrometry and NMR after the active compound was isolated and purified. Deinoxanthin exhibited an obvious inhibitory effect on algal growth, and showed algicidal activity against A. tamarense with an EC50 of 5.636 mu g/mL with 12 h treatment time. Based on the unique structure and characteristics of deinoxanthin, the content of reactive oxygen species (ROS) increased after 0.5 h exposure, the structure of organelles including chloroplasts and mitochondria were seriously damaged. All these results firstly confirmed that deinoxanthin as the efficient and eco-environmental algicidal compound has potential to be used for controlling harmful algal blooms through overproduction of ROS. (C) 2015 Elsevier B.V. All rights reserved. |
| Databáze: | OpenAIRE |
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