Intrafamilial spread of hepatitis C virus
| Autor: | R. Rodríguez García, F. Sánchez San Román, Carmen Alvarez Navascués, A. Suárez González, F. Menéndez Tévar, R. Pérez Alvarez, L. Rodrigo Saez, S. Riestra Menendez |
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| Rok vydání: | 1991 |
| Předmět: |
Microbiology (medical)
Adult Male medicine.medical_specialty Cirrhosis Adolescent Hepatitis C virus Blood Donors Hepacivirus medicine.disease_cause Gastroenterology Virus Risk Factors Internal medicine medicine Carcinoma Prevalence Humans Hepatitis Antibodies Index case Aged Hepatitis Family Health biology business.industry Age Factors virus diseases General Medicine Hepatitis C Antibodies Middle Aged medicine.disease Hepatitis C digestive system diseases Infectious Diseases Spain Hepatocellular carcinoma Immunology biology.protein Female Antibody business |
| Zdroj: | Infection. 19(6) |
| ISSN: | 0300-8126 |
| Popis: | We studied the prevalence of antibodies against hepatitis C virus (anti-HCV) among 530 household contacts of 225 anti-HCV-positive subjects (index cases). Twenty-six (4.9%) relatives had anti-HCV, a proportion higher than that found among blood donors (175 of 22,435; 0.78%) (p less than 0.001). We did not find any differences regarding the type of relation with the index case (sexual or nonsexual). The prevalence of anti-HCV increased with the age of the relatives, with the contact time with the index case, and with the time of exposure to HCV. On the other hand, the anti-HCV was associated mainly with the existence of cirrhosis or hepatocellular carcinoma in the patient. We concluded that intrafamilial transmission may be an important mechanism in the spread of HCV. |
| Databáze: | OpenAIRE |
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