Detecting spatial-temporal cluster of hand foot and mouth disease in Beijing, China, 2009-2014
Autor: | Xiaoli Wang, Xitai Li, Da Huo, Zhiyong Gao, Quanyi Wang, Jie Li, Haikun Qian, Baiwei Liu, Xiaona Wu, Lei Jia, Yi Tian |
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Rok vydání: | 2016 |
Předmět: |
Male
0301 basic medicine China medicine.medical_specialty Veterinary medicine Epidemiology Spatiotemporal medicine.disease_cause 03 medical and health sciences 0302 clinical medicine Beijing Pregnancy Interquartile range Enterovirus 71 Animals Humans Medicine Spatial distribution 030212 general & internal medicine Epidemics Disease burden Enterovirus Space–time clustering Spatial Analysis biology business.industry Incidence Incidence (epidemiology) Infant biology.organism_classification Hand foot and mouth disease 030104 developmental biology Infectious Diseases Child Preschool Female Hand Foot and Mouth Disease business Cartography Foot (unit) Research Article |
Zdroj: | BMC Infectious Diseases |
ISSN: | 1471-2334 |
DOI: | 10.1186/s12879-016-1547-6 |
Popis: | The incidence of hand, foot, and mouth disease (HFMD) is extremely high, and has constituted a huge disease burden throughout Beijing in recent years. This study aimed to determine the spatiotemporal distribution and epidemic characteristics of HFMD. Descriptive statistics was used to analyze the data and estimate the epidemic peaks in 2009–2014. Space–time scanning detected spatiotemporal clusters and identified high-risk locations. Global and local Moran’s I statistics were used to measure the spatial autocorrelation. Geocoding was performed in ArcGIS, based on the present address codes of the patients and the centroids of the towns. Maps were created in ArcGIS to show the geographic spread of HFMD. In total, 220,451probable cases of HFMD were reported in Beijing between January 2009 and December 2014: 12,749 (5.78 %) were laboratory confirmed, and 35 (0.02 %) were fatal. The median age of reported cases was 3.12 years (interquartile range 1.96–4.39). Coxsackievirus A16 (CV-A16), enterovirus 71 (EV-A71), and other enteroviruses accounted for 39.31, 35.36, and 25.33 % of the 12,749 confirmed cases, respectively. Many more severe cases were caused by EV-A71 (χ 2 = 186.41, df = 1, P |
Databáze: | OpenAIRE |
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