Association of Elevated Urinary Cadmium with Urinary Stone, Hypercalciuria and Renal Tubular Dysfunction in the Population of Cadmium-Contaminated Area
| Autor: | Patchanrin Pingmuangkaew, Sukumarn Niyomtam, Suwadee Meemark, Orathai Tangvarasittichai, Surapon Tangvarasittichai, Yingyot Kaewnate |
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| Rok vydání: | 2012 |
| Předmět: |
Adult
Male medicine.medical_specialty Health Toxicology and Mutagenesis Urinary system Hypercalciuria Population Urology urologic and male genital diseases Toxicology Renal tubular dysfunction medicine Humans Renal Insufficiency Chronic education Aged education.field_of_study Proteinuria business.industry Environmental Exposure General Medicine Environmental exposure Middle Aged medicine.disease Pollution female genital diseases and pregnancy complications Urinary calcium Calcium Environmental Pollutants Female Urinary Calculi medicine.symptom business Cadmium Kidney disease |
| Zdroj: | Bulletin of Environmental Contamination and Toxicology. 89:1120-1124 |
| ISSN: | 1432-0800 0007-4861 |
| DOI: | 10.1007/s00128-012-0856-8 |
| Popis: | Excessive urinary calcium is the major risk of renal tubular dysfunction and urinary stone formation. We examined the association of elevated urinary cadmium with urinary stones and chronic kidney disease (CKD) in 1,085 study residents of 13 cadmium-contaminated villages. Elevated urinary cadmium was significantly correlated with urinary stone and CKD. Elevated urinary cadmium appeared to increase risk of urinary stone and CKD; ORs and 95 % CIs were 2.73 (1.16, 6.42) and 3.73 (2.50, 5.57) after adjusting for other co-variables. This study revealed that elevated urinary stone and CKD induced by cadmium might increase the risk of urinary stone and CKD. |
| Databáze: | OpenAIRE |
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