An exploratory, large-scale study of pain and quality of life outcomes in cancer patients with moderate or severe pain, and variables predicting improvement
| Autor: | Luis Zugazabeitia, Mariano Provencio, Miguel A. Núñez, Iker López, Juan L. Martí-Ciriquián, Jorge Contreras, Susana Traseira, Constanza Maximiano, Cristina San Martín, Michael Herdman |
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| Přispěvatelé: | UAM. Departamento de Medicina |
| Rok vydání: | 2018 |
| Předmět: |
Male
Cancer Treatment lcsh:Medicine Anxiety Pathology and Laboratory Medicine 0302 clinical medicine Quality of life Neoplasms Breast Tumors Medicine and Health Sciences Longitudinal Studies 030212 general & internal medicine lcsh:Science Pain Measurement Aged 80 and over First episode Multidisciplinary Pharmaceutics Depression Middle Aged Poor baseline humanities Oncology 030220 oncology & carcinogenesis Female Anatomy medicine.symptom Research Article Clinical Oncology Adult QoL medicine.medical_specialty Medicina Visual analogue scale Pain Cancer Chemotherapy 03 medical and health sciences Signs and Symptoms Breast cancer Drug Therapy Diagnostic Medicine Breast Cancer medicine Chemotherapy Humans Pain Management Anxiety and depression Brief Pain Inventory Neuropathic Pain Aged Performance status business.industry lcsh:R Cancers and Neoplasms Biology and Life Sciences Cancer patients medicine.disease Logistic Models Head and Neck Cancers Quality of Life Physical therapy lcsh:Q Observational study Clinical Medicine business Head Neck |
| Zdroj: | PLoS One r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau instname PLoS ONE, Vol 13, Iss 4, p e0193233 (2018) Biblos-e Archivo. Repositorio Institucional de la UAM r-ISABIAL. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica y Sanitaria de Alicante PLoS ONE |
| ISSN: | 1932-6203 |
| DOI: | 10.1371/journal.pone.0193233 |
| Popis: | Background There have been few large-scale, real world studies in Spain to assess change in pain and quality of life (QOL) outcomes in cancer patients with moderate to severe pain. This study aimed to assess changes on both outcomes after 3 months of usual care and to investigate factors associated with change in QoL. Patients and methods Large, multi-centre, observational study in patients with lung, head and neck, colorectal or breast cancer experiencing a first episode of moderate to severe pain while attending one of the participating centres. QoL was assessed using the EuroQol-5D questionnaire and pain using the Brief Pain Inventory (BPI). Instruments were administered at baseline and after 3 months of follow up. Multivariate analyses were used to assess the impact of treatment factors, demographic and clinical variables, pain and other symptoms on QoL scores. Results 1711 patients were included for analysis. After 3 months of usual care, a significant improvement was observed in pain and QoL in all four cancer groups (p Financial support for this research was provided by Mundipharma Pharmaceuticals S.L. |
| Databáze: | OpenAIRE |
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