Plasma L-ENK, AVP, ANP and serum gastrin in patients with syndrome of Liver-Qi-stagnation
Autor: | Guo-Lin Chen, Ze-Qi Chen, Yu-Qiu Zhao, Lin-Jie Shi, Xue-Wen Li |
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Jazyk: | angličtina |
Rok vydání: | 1999 |
Předmět: |
endocrine system
medicine.medical_specialty business.industry Gastroenterology Healthy subjects Chronic gastritis food and beverages General Medicine Traditional Chinese medicine medicine.disease Combined Traditional And Modern Medicine Pathophysiology Serum gastrin Endocrinology Gastrin levels Internal medicine medicine In patient business human activities hormones hormone substitutes and hormone antagonists Gastrin |
Popis: | AIM:To investigate the pathophysiologic basis of syndrome of Liver-Qi stagnation and parameters for clinical differentiation.METHODS:Plasma L-ENK, AVP, ANP and serum gastrin were determined by RIA in 84 patients with neurasthenia, mastodynia,chronic gastritis, and chronic cholecystitis presenting the same syndrome of Liver-Qi stagnation in traditional Chinese medicine (TCM). Healthy subjects served as controls in comparison with patients having the same syndrome but with different diseases.RESULTS:Among the patients with Liver-Qi stagnation, the plasma L-ENK, ANP and gastrin levels were 38.83ng/L ± 6.32ng/L, 104.11ng/L ± 29.01ng/L and 32.20ng/L ± 6.68ng/L, being significantly lower than those in the healthy controls (P0.01, t = 3.34, 6.17, 4.48). The plasma AVP of the patient group (52.82ng/L ± 19.09ng/L) was significantly higher than that of the healthy controls (P0.01, t = 5.79 =. The above changes in patients having the same symptom complex but different diseases entities showed no significant differences, P0.05.CONCLUSION:The syndrome of Liver-Qi stagnation is closely related to the emotional modulatory abnormality of the brain, with decrease of plasma L-ENK, ANP and gastrin, and increase of plasma AVP as the important pathophysiologic basis. |
Databáze: | OpenAIRE |
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