Prognostic of NT-proBNP in heart failure patients with preserved, mid and reduced ejection fraction
| Autor: | Anthony Gutiérrez, Helio Manuel Grullón Rodríguez, Reynie Leonel Reinoso Gonella, Yasmín Céspedes Batista, Lisnaldy Ramírez Osoria, Amada Álvarez |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
Medicine (General)
medicine.medical_specialty medicine.drug_class heart failure Logistic regression R5-920 Internal medicine Natriuretic peptide Medicine cardiovascular diseases Ejection fraction business.industry cardiovascular Mortality rate Retrospective cohort study General Medicine Plasma levels medicine.disease mortality NT-proBNP Heart failure Cardiology Public aspects of medicine RA1-1270 Heart failure with preserved ejection fraction business prognostic hormones hormone substitutes and hormone antagonists |
| Zdroj: | Ciencia y Salud, Vol 5, Iss 3 (2021) |
| ISSN: | 2613-8824 2613-8816 1001-5000 |
| DOI: | 10.22206/cysa.2021.v5i3.pp5-12 |
| Popis: | Objective. The prognostic value of N-terminal procerebral natriuretic peptide (NT-proBNP) in patients with heart failure (HF) is well established. In contrast, its role as an early predictor of mortality in patients hospitalized for heart failure with preserved ejection fraction (HF-EF) and heart failure with reduced ejection fraction (HF-EF) is less well documented. Therefore, the objective of this study is to evaluate the usefulness and prognostic value of plasma NT-proBNP in these patients. Method. This retrospective observational study included 620 patients admitted for acute heart failure, classified into 3 groups according to their left ventricular ejection fraction (LVEF): HF-EF (LVEF ≥ 50%), HF-mEF (heart failure with ejection fraction mean) (LVEF 35-49%) and HF-rEF (LVEF 15001pg / ml (30.6%). The mortality rate increased significantly in patients with NT-proBNP concentrations > 15001 pg / ml (40%) and decreased with NT-proBNP levels |
| Databáze: | OpenAIRE |
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