Unexpected borderline malignant and malignant smooth muscle cell tumors of the uterine corpus in women treated with LH-RH analogues

Autor: Marinus P.M. Hermans, Carla C.A.P. Wauters, Frank Smedts, Bram ter Harmsel
Rok vydání: 1995
Předmět:
Zdroj: European Journal of Obstetrics & Gynecology and Reproductive Biology. 62:257-259
ISSN: 0301-2115
DOI: 10.1016/0301-2115(95)02192-a
Popis: In this report, two cases of uterine smooth muscle cell tumors, one of uncertain malignant potential and one clearly malignant, are described in women treated for prolonged periods with luteinizing hormone-releasing hormone (LH-RH) analogues. Due to lengthy monitoring of LH-RH therapy, surgical intervention and histologic classification of these tumors was late in the course of disease, resulting in a delay in definite treatment. The risk to these women is discussed. The effects of LH-RH analogue therapy on fibroids is reviewed. Suggestions are put forward for monitoring LH-RH analogue therapy.
Databáze: OpenAIRE