Decline in ventricular function as a result of general anesthesia in pediatric heart transplant recipients
| Autor: | Shahryar M. Chowdhury, Marc Hassid, Carolyn L. Taylor, Justin J. Elhoff, Ryan J. Butts, Andrew Savage, Andrew M. Atz |
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| Rok vydání: | 2016 |
| Předmět: |
Male
Cardiac function curve medicine.medical_specialty Adolescent Systole Heart Ventricles medicine.medical_treatment Systolic function Anesthesia General 030204 cardiovascular system & hematology 030230 surgery Graft function Article Biventricular function Young Adult 03 medical and health sciences 0302 clinical medicine Diastole Internal medicine medicine Humans Ventricular Function Child Anesthetics Cardiac catheterization Transplantation Ventricular function business.industry Infant Newborn Infant Echocardiography Child Preschool Anesthesia Pediatrics Perinatology and Child Health Anesthetic Cardiology Heart Transplantation Female business medicine.drug |
| Zdroj: | Pediatric Transplantation. 20:1106-1110 |
| ISSN: | 1397-3142 |
| Popis: | Echocardiography is frequently performed under anesthesia during procedures such as cardiac catheterization with EMB in pediatric HTx recipients. Anesthetic agents may depress ventricular function, resulting in concern for rejection. The aim of this study was to compare ventricular function as measured by echocardiography before and during GA in 17 pediatric HTx recipients. Nearly all markers of ventricular systolic function were significantly decreased under GA, including EF (−4.2% ±1.2, P < .01) and RV FAC (−0.05 ± 0.02, P = .04). Subjects in the first post-transplant year (n = 9) trended toward a more significant decrease in EF vs those beyond the first post-transplant year (n = 8; −6.0% ±1.2 vs −2.1 ± 2.0, P = .1). This information quantifies a decline in biventricular function that should be expected in pediatric HTx recipients while under GA and can assist the transplant clinician in avoiding unnecessary treatment of transient GA-induced ventricular dysfunction. |
| Databáze: | OpenAIRE |
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