The effect of contact angles and capillary dimensions on the burst frequency of super hydrophilic and hydrophilic centrifugal microfluidic platforms, a CFD study
| Autor: | Fatimah Ibrahim, Marc J. Madou, Amin Kazemzadeh, Shuisheng He, P. Ganesan |
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| Rok vydání: | 2013 |
| Předmět: |
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Materials science Capillary action Microfluidics lcsh:Medicine 02 engineering and technology Computational fluid dynamics Microvalves 01 natural sciences Surface tension Contact angle Fabrication Rotating-Disk Total Analysis Systems Surface-Tension Fluid dynamics Volume of fluid method Physical Sciences and Mathematics lcsh:Science Multidisciplinary business.industry Flow 010401 analytical chemistry Passive Valves lcsh:R Life Sciences Mechanics Microfluidic Analytical Techniques Models Theoretical 021001 nanoscience & nanotechnology Aspect ratio (image) 0104 chemical sciences Micro Check Valves lcsh:Q 0210 nano-technology business Stop Valves Research Article |
| Zdroj: | PLoS ONE PLoS ONE, Vol 8, Iss 9, p e73002 (2013) Kazemzadeh, Amin; Ganesan, Poo; Ibrahim, Fatimah; He, Shuisheng; Madou, Marc J; & Han, Arum. (2013). The Effect of Contact Angles and Capillary Dimensions on the Burst Frequency of Super Hydrophilic and Hydrophilic Centrifugal Microfluidic Platforms, a CFD Study. PLoS ONE, 8(9), e73002. doi: 10.1371/journal.pone.0073002. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/0tn7k4x6 |
| ISSN: | 1932-6203 |
| DOI: | 10.1371/journal.pone.0073002. |
| Popis: | This paper employs the volume of fluid (VOF) method to numerically investigate the effect of the width, height, and contact angles on burst frequencies of super hydrophilic and hydrophilic capillary valves in centrifugal microfluidic systems. Existing experimental results in the literature have been used to validate the implementation of the numerical method. The performance of capillary valves in the rectangular and the circular microfluidic structures on super hydrophilic centrifugal microfluidic platforms is studied. The numerical results are also compared with the existing theoretical models and the differences are discussed. Our experimental and computed results show a minimum burst frequency occurring at square capillaries and this result is useful for designing and developing more sophisticated networks of capillary valves. It also predicts that in super hydrophilic microfluidics, the fluid leaks consistently from the capillary valve at low pressures which can disrupt the biomedical procedures in centrifugal microfluidic platforms. |
| Databáze: | OpenAIRE |
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