Long-term prognosis of esophageal variceal cases treated with injection sclerotherapy
| Autor: | Kiyoshi Ashida, Saburo Ohshiba, Ichiro Hirata, Akio Matsumoto, Hogen Tei, Naofumi Osaka, Hirofumi Miyoshi |
|---|---|
| Rok vydání: | 1989 |
| Předmět: |
Adult
medicine.medical_specialty Time Factors Digestive System Diseases medicine.medical_treatment Hemorrhage Esophageal and Gastric Varices Injections Esophageal varices Recurrence Injection sclerotherapy Internal medicine Sclerotherapy medicine Humans Survival rate Aged business.industry Gastroenterology Middle Aged Hepatology Prognosis medicine.disease Colorectal surgery Surgery Hemostasis business Abdominal surgery |
| Zdroj: | Gastroenterologia Japonica. 24:469-475 |
| ISSN: | 0435-1339 |
| Popis: | One hundred fifty-two patients with esophageal varices underwent a total of 485 injection sclerotherapy procedures (mean, 3.2 times per each case). During 5 years of observation, 20 cases (13.2%) died following injection sclerotherapy. The 3-year survival rates, based on the Kaplan-Meier method, were 42% for emergency cases, 75% for elective cases and 90% for prophylactic cases. Significant differences (P less than 0.05) by the generalized Wilcoxon test were observed in the survival rates between emergency cases and prophylactic cases, and also between elective cases and prophylactic cases. Two cases (8.6%) of failure to control acute hemostasis were experienced. Twenty cases of bleeding after sclerotherapy were experienced, and 8 died of bleeding. The three-year bleeding rate according to the Kaplan-Meier method was 59% for emergency cases, 25% for elective cases and 7% for prophylactic cases. A significant difference (P less than 0.05) by the generalized Wilcoxon test was observed in the bleeding rate between elective cases and prophylactic cases. Non-bleeding rate (100%-bleeding rate) after sclerotherapy showed almost the same values as the survival rate. These results indicate that upper digestive tract hemorrhage influences the prognosis of patients after sclerotherapy. |
| Databáze: | OpenAIRE |
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