| Autor: |
Arti Parmar, Donald Hulme, Daniel Hacking, Gordon Shymko, Milan Dragovic, Grace Terina, Flavie Waters |
| Rok vydání: |
2022 |
| Předmět: |
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| Zdroj: |
Australasian psychiatry : bulletin of Royal Australian and New Zealand College of Psychiatrists. 30(1) |
| ISSN: |
1440-1665 |
| Popis: |
Objective: Aripiprazole is often prescribed to young people, although there remain unanswered questions about its effects on weight gain. This study undertook a meta-analysis of weight gain occurring in young people with early psychosis who were prescribed aripiprazole. Method: A systematic search was conducted for studies reporting on aripiprazole and weight change in young people with a psychotic disorder. A meta-analysis integrated the data into an estimate of effect size. Results: Eleven studies met the inclusion criteria amounting to 886 participants (mean age 18 years). The results showed significant weight gain averaging 2.7 kg. These increases were associated with a longer duration of exposure to aripiprazole but not a higher dosage. Conclusions: The results highlight the importance of regular patient monitoring and the early implementation of interventions to manage antipsychotic-related weight gain. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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