Risk and Prognostic Factors in Perinatal Hemorrhagic Stroke
| Autor: | Saim Açıkgözoğlu, Fatma Tuba Köseoğlu, Mehmet Sinan İyisoy, Hüseyin Altunhan, Ahmet Sami Güven, Hüseyin Çaksen |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Mechanical ventilation
Pediatrics medicine.medical_specialty Neonatal sepsis Respiratory distress business.industry medicine.medical_treatment Mortality rate perinatal stroke Hemorrhage medicine.disease infant Perinatal asphyxia Cerebral palsy medicine Small for gestational age Original Article Neurology. Diseases of the nervous system Neurology (clinical) RC346-429 business Stroke |
| Zdroj: | Annals of Indian Academy of Neurology Annals of Indian Academy of Neurology, Vol 24, Iss 2, Pp 227-233 (2021) |
| ISSN: | 1998-3549 0972-2327 |
| Popis: | Background: Perinatal stroke encompasses a heterogeneous group of focal neurological injuries early in brain development. In this study, we aimed to compare risk and prognostic factors in preterm and term infants with perinatal hemorrhagic stroke (PHS). Patients and Methods: The study includes 66 infants with PHS. The infants were evaluated for demographic characteristics, fetal and maternal risk factors, perinatal events, clinical and neuroimaging findings, complications, and sequales. Results: Of 66 infants with PHS, 44 (66.70%) were preterm and 22 (33.30%) were term infants. Primiparity, mucosal bleeding, and multiple lobes involvement were more common in term infants than preterm infants (P < 0.05); however, respiratory insufficiency, neonatal sepsis, perinatal asphyxia, respiratory distress syndrome, use of invasive mechanical ventilation, use of noninvasive mechanical ventilation, and prolonged hospitalization were more common in preterm infants than term infants (P < 0.05). Eight (12.12%) infants died during infancy period. Small for gestational age and mucosal bleeding were more common in infants who are dead than those alive (P < 0.05). Forty-two (63.63%) infants were followed. Cerebral palsy and/or epilepsy and/or hydrocephalus were diagnosed in 36 (85.72%) infants during follow-up. Conclusion: Our findings showed that PHS was much more common in preterm infants. Mucosal bleeding and multiple lobes involvement were more common in term infants. PHS has high morbidity and mortality rates. Small for gestational age and mucosal bleeding were more common in infants who are dead. |
| Databáze: | OpenAIRE |
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