Exclusion criteria: Evaluating the impact of enrollment requirements in SEER‐Medicare research

Autor: Marianna V. Papageorge, Sing Chau Ng, Teviah E. Sachs, Kelly M. Kenzik
Rok vydání: 2022
Předmět:
Zdroj: Journal of the American Geriatrics Society. 70:3593-3597
ISSN: 1532-5415
0002-8614
DOI: 10.1111/jgs.18017
Popis: Enrollment criteria are routinely utilized in patient selection in SEER-Medicare but little is known about how this may be impacting research outcomes. This study evaluated demographics and survival among pancreatic cancer patients who are included and excluded from SEER-Medicare analyses.Patients ≥66 years old with pancreatic cancer were identified (SEER-Medicare, 2008-2015). Two patient cohorts were compared: included (continuous enrollment in Medicare Parts A and B and no enrollment in Medicare Advantage), and excluded. Mortality was assessed using a Standardized Mortality Ratio.Among 49,017 patients with pancreatic cancer, 59.5% were in the included cohort. The excluded cohort was younger (median age 74 vs. 77) with more male (49.9% vs. 47.8%), non-white (33.0% vs. 21.3%) and urban-dwelling patients (91.0% vs. 85.0%). Those excluded had a higher mortality risk (SMR 1.06, 95%CI 1.04-1.07).There are significant differences in patient demographics and mortality among those who are and are not routinely included in SEER-Medicare analyses and our study provides a critical opportunity to quantify this potential bias.
Databáze: OpenAIRE
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