Effect of maternal age on uterine flow impedance
| Autor: | Saemundur Gudmundsson, Michael Abdlenoor, Tone Kristin Bergersen, Jouko Pirhonen, Marius Dubiel |
|---|---|
| Rok vydání: | 2005 |
| Předmět: |
Adult
Aging medicine.medical_specialty Adolescent Uterus Normal pregnancy Ultrasonography Prenatal Pregnancy medicine.artery Electric Impedance Humans Medicine Radiology Nuclear Medicine and imaging Uterine artery Gynecology business.industry Obstetrics Confounding Gestational age Blood flow Middle Aged Laser Doppler velocimetry Parity Cross-Sectional Studies medicine.anatomical_structure Regional Blood Flow Female business Parity (mathematics) Maternal Age |
| Zdroj: | Journal of Clinical Ultrasound. 33:14-17 |
| ISSN: | 1097-0096 0091-2751 |
| Popis: | Purpose. This study was conducted to determine possible maternal age-related changes in uterine artery impedance in normal late pregnancy. Patients and Methods. In a cross-sectional design study, Doppler velocimetry of the uterine vessels was performed in 884 pregnant women with normal, late, singleton pregnancies. We hypothesized that maternal age is associated with changes in uterine blood flow Doppler parameters. We tested for univariate associations and for an adjusted relationship between these factors using a multivariate model to control for confounders. Results. We found a statistically significant, nonlinear relationship between mean uterine artery impedance (pulsatility index) and maternal age, with an increase of the pulsatility index in women above the age of 35. This association continued to be significant even when adjusted for gestational age and parity as confounders. Conclusions. In normal pregnancy, an increase in uterine artery impedance was noted in women above the age of 35. This finding may be related to the physiologic process of aging and may partly explain why pregnancies in older women are associated with diverse complications more often than those in younger women. (Less) |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Plný text