Difficulties of Mobilization and Harvesting of Hematopoietic Stem Cells in Heavily Pre-Treated Patients
Autor: | Erzsébet Lázár, Judit-Beáta Köpeczi, Enikő Kakucs, István Benedek, Szende Jakab, Annamária Pakucs, Cezara Tudor |
---|---|
Jazyk: | angličtina |
Rok vydání: | 2017 |
Předmět: |
Oncology
medicine.medical_specialty Mobilization business.industry lcsh:R plerixafor lcsh:Medicine autologous transplantation 03 medical and health sciences Haematopoiesis 0302 clinical medicine immune system diseases 030220 oncology & carcinogenesis Internal medicine hemic and lymphatic diseases Medicine Stem cell business mobilization 030215 immunology |
Zdroj: | Journal of Interdisciplinary Medicine, Vol 2, Iss 1, Pp 41-44 (2017) |
ISSN: | 2501-8132 |
Popis: | This study presents a new method of combined growth factor mobilization with increased dose (15 μg/kg) of filgrastim and standard mono dose of plerixafor in subjects with multiple myeloma, Hodgkin or non-Hodgkin lymphoma. Efficient mobilization is a key factor in the treatment of this group of patients, because autologous transplantation can be performed in cases in which we succeed to obtain a minimally sufficient number of stem cells. Autologous stem cell transplantation is included in the current standard treatment of multiple myeloma and in the relapsed cases of lymphomas. |
Databáze: | OpenAIRE |
Externí odkaz: |