Prolonged multimodal fasting modulates periodontal inflammation in female patients with metabolic syndrome: A prospective cohort study
| Autor: | Nico Steckhan, Theresa Keller, Daniela Hoedke, Henrik Dommisch, Andreas Michalsen, Christina Laetitia Pappe, Søren Jepsen, Geralinde Rauch |
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| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Male
medicine.medical_specialty Waist fasting Bleeding on probing bleeding on probing Gastroenterology metabolic syndrome C-reactive protein 03 medical and health sciences 0302 clinical medicine Weight loss Internal medicine medicine periodontal inflammation Humans 030212 general & internal medicine Prospective Studies Prospective cohort study Inflammation biology business.industry 030206 dentistry medicine.disease Blood pressure gingival crevicular fluid biology.protein Periodontics Female medicine.symptom Metabolic syndrome business 600 Technik Medizin angewandte Wissenschaften::610 Medizin und Gesundheit::610 Medizin und Gesundheit Lipoprotein |
| Popis: | AIM To determine the potential anti-inflammatory effect of a multimodal periodic fasting programme on surrogate parameters of periodontal inflammation in hospitalized patients diagnosed for metabolic syndrome (MetS). MATERIAL AND METHODS A total of 47 patients were recruited and hospitalized in an integrative ward for an intensified two-week multimodal fasting, diet and lifestyle programme. Patients were periodontally examined at baseline (t1), after the 2-week fasting protocol (t2) and, subsequently, 4 months after fasting (t3). The following parameters were determined: periodontal screening index (PSI), bleeding on probing (BOP), gingival crevicular fluid volume (GCF), plaque index (PI), C-reactive protein (CRP), blood pressure (BP), waist circumference (WC), fasting glucose (FGLU), triglycerides (TRG), high-density lipoprotein (HDL) and HbA1c. RESULTS A total of 28 female and 8 male patients fulfilled the defined criteria for MetS and were analysed separately by gender. At t2, BOP and GCF were reduced when compared to t1 (median: t2 = 39; t1 = 33.1%; p |
| Databáze: | OpenAIRE |
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